Vitamin-A Flashcards

1
Q

Inactive form of vitamin A?

A

Beta carotene.

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2
Q

Compounds having vitamin A activity are called?

A

Retinoids.

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3
Q

Whose trans variety makes vitamin A1?

A

Retinal.

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4
Q

How can vitamin A1 can be converted to vitamin A2?

A

By adding extra double bond in vitamin A1.

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5
Q

Major absorption site of vitamin A?

A

Intestine.

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6
Q

Which form of Vitamin A is absorbed?

A

Retinal.

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7
Q

Without which substances vitamin A can’t be absorbed?

A

Fats and bile salts.

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8
Q

In which form vitamin is stored in liver?

A

Retinal palmitate.

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9
Q

With which substance trans retinal is transported from liver to peripheral tissues?

A

Retinal binding protein (RBP).

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10
Q

Membrane protein found in photoreceptor cells of retina ?

A

Rhodopsin.

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11
Q

Which photosensitive cell is for Dim light?

A

Rods.

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12
Q

What is rhodopsin of rod made up of?

A

11-cis retinal + opsin.

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13
Q

How many rods are there per eye?

A

120 million.

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14
Q

Deficiency of 11-cis retinal will cause?

A

Dark adaptation time increases.

Night blindness.

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15
Q

Which protein is found in cones?

A

Conopsin .

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16
Q

Which photosensitive cell is responsible for bright light?

A

Cones.

17
Q

Deficiency of cones cause?

A

Colour blindness.

18
Q

No. of cones per eye?

A

6 million.

19
Q

Which synthetic variant of vitamin A prevents acne ?

A

Isoretinone.

20
Q

In which case, conjunctiva becomes dry and get keratinised and leads to keratinisation of cornea?

A

Xerophthalmia.

21
Q

In which case, grey- whitish plaques are seen adherent to conjunctiva?

A

Bitot spots.

22
Q

If xerophthalmia persists for long term, leads to softening of cornea , what is the diagnosis?

A

Keratomalacia.