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Virology > Virology Final Pathogenesis Facts > Flashcards

Virology Final Pathogenesis Facts Flashcards

1
Q

African Swine Fever Virus tropism

A

monocytes/macrophages

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2
Q

BHV-1 latency

A

tonsils, lymphoid tissue
trigeminal ganglion
sacral ganglion

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3
Q

BHV-5 latency

A

trigeminal ganglion, midbrain, thalamus, olfactory nerve

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4
Q

EHV-1 latency

A

trigeminal ganglion
lymphoid tissue

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5
Q

EHV-3 latency

A

latent in sacral ganglion

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6
Q

Pseudorabies Virus eradicated in what species? latency where?

A

eradicated in domestic swine
cranial nerve ganglion

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7
Q

CHV-1 latency

A

sacral ganglion

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8
Q

FHV-1 latency

A

trigeminal ganglion

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9
Q

cervine adenovirus differential diagnostics

A

Epizootic Hemorrhage Disease
Malignant Catarrhal Fever

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10
Q

Canine Parvovirus 2 tropism

A

myocardial cells
rapidly dividing cells

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11
Q

Feline Panleukopenia Virus tropism

A

external granular layer of cerebellum

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12
Q

Porcine Parvovirus often co-infected with ______

A

Porcine Circovirus 2

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13
Q

CAV-1 and CAV-2

A

CAV-2 cross protective immunity for CAV-1, shed in urine = 2nd vx and herd immunity

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14
Q

CPV-1 and CPV-2

A

genetically distinct
NO cross-protective immunity

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15
Q

Bovine Papillomairus 1,2,3 tropism

A

keratinocytes and fibroblasts

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16
Q

Bovine Papillomavirus 4,5,6 tropism

A

keratinocytes

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17
Q

Equine Sarcoids often have _____ genomic sequences

A

BPV-1,2
horses are non-permissive host

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18
Q

FeLV strains & tropism

A

A - horizontally transmittable
B - endogenous + A = recombinant strain
endogenous - non-pathogenic

lymphocytes, monocytes, salivary epithelium

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19
Q

FIV tropism and strains

A

CD4/CD8 T cells
A & B most common, B less pathogenic

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20
Q

Bovine Leukemia Virus tropism

A

B lymphocytes

21
Q

EIA tropism

A

macrophages

22
Q

Orbivirus tropism
Epizootic Hemorrhage Disease Virus
Blue Tongue Virus
African Horse Sickness Virus

A

reticuloendothelial cells (macrophages, dendritic cells)

23
Q

Infectious Bursal Disease Virus tropism

A

lymphotropic for B cells

24
Q

Rabies virus inclusion bodies

A

eosinophilic intracytoplasmic inclusion bodies “negri bodies”

25
Q

VSV tropism

A

epithelial cells

26
Q

Swine Influenza enzootic subtypes and sporadic subtypes

A

enzootic H1 and H3
sporadic H2,4,5,7,9

27
Q

Equine Influenza subtypes

A

H3N8 (A2)
H7N7 (A1)

28
Q

Canine Influenza subtype

A

H3N8

29
Q

Rinderpest tropism

A

lymphocytes, macrophages, dendritic cells, endothelial cells

30
Q

Peste de Petitis Ruminant Virus has high mortality in ______

A

goats

31
Q

what stage of Avian Paramyxovirus-1 is used in the modified live vaccine? which is the most severe?

A

lentogenic - mild/subclinical

most severe is viscerotropic velogenic

32
Q

Hendra virus tropism

A

endothelial cells

33
Q

Nipah virus tropism

A

endothelial cells & neurons

34
Q

Borna Disease Virus replications in what cells

A

neurons, astrocytes, oligodendrocytes
“Joest-degen bodies”

35
Q

what makes Picornaviridae viruses (e.g. FMD) have high mutation rates

A

lack of RNA proof-reading

36
Q

FMD virus targets what cells

A

epithelial/keratinocytes

37
Q

West Nile Virus replicates in what cells

A

keratinocytes, Langerhans, Dendritc cells

38
Q

BVDV biotypes and cell tropism

A

non-cytopathic (most common)
cytopathic (CPE)

rapidly dividing cells - lymphocytes, monocytes, macrophages, epithelial cells

39
Q

classical swine fever virus tropism

A

monocytes, macrophages, endothelial

40
Q

equine arteritis virus tropism

A

macrophages, monocytes, lymphocytes

41
Q

Porcine Reproductive and Respiratory Syndrome Virus tropism

A

alveolar macrophages

42
Q

Porcine Respiratory Coronavirus mutant of ____

A

TGEV - deletion of E2 spike protein

43
Q

when did PEDV emerge in US

A

April 2013

44
Q

FIP mutant of _____
mutates in _____
replicates in ______

A

feline enteric coronavirus
mutates in intestinal epithelium
replicates in macrophages

45
Q

herpesvirus inclusion bodies

A

eosinophilic intranuclear inclusion bodies

46
Q

parvovirs inclusion bodies

A

intranuclear inclusion bodies

47
Q

reoviridae inclusion bodies

A

intracytoplasmic inclusion bodies

48
Q

Paramyxoviridae inclusion bodies

A

eosinophilic intracytoplasmic & intranuclear inclusion bodies

Virology (16 decks)

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