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BacT, Virology, Parasit > Virology Exam 2 - Papillomaviridae & Polyomaviridae > Flashcards

Virology Exam 2 - Papillomaviridae & Polyomaviridae Flashcards

1
Q

Papillomaviridae
SHAPE
ENVELOPED/NON-ENVELOPED
DNA/RNA

A

icosahedral
non-enveloped
circular dsDNA

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2
Q

Papillomaviridae replication and oncoproteins

A

early genes that regulat regulation (oncoproteins)
late genes encode structural proteins

E7 (degrades retinoblastoma proteins)
E6 (degrades p53)

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3
Q

Bovine Papillomatosis
HOST
DISEASE

A

bovine - yearling, calves
papillomas, fibropapillomas

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4
Q

BPV 1,2,3

A

fibropapillomas

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5
Q

BPV 2

A

bladder neoplasms, enzootic hematuria with bracken fern (quercetin ingestion)

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6
Q

BPV4

A

papillomas in GI, neoplasms

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7
Q

BPV 5,6

A

papillomas on teats

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8
Q

Equine Papillomatosis
HOST
DISESE

A

equine
cutaneous papillomas, warts on muzzles/ears/eyes/genitals, aural plaques, nodular on inner pinna

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9
Q

Equine Sarcoids
HOST
DISEASE

A

equine
neoplasm, fibroblastic tumor on head/limbs/ventral body

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10
Q

____ is not host specific and _____ genomic sequences are often in many equine sarcoids

a horse is a _____ for ______

A

equine sarcoid
BPV1,2

non-permissive host
BPV

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11
Q

Canine Papillomatosis
HOST
DISEASES

A

canines
oral papillomas, endophytic papillomas, pigmented cutaneous placques (pugs), squamous cell carcinoma (dogs w/ SCID)

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12
Q

Avian Papillomaviruses
HOST
DISEASE

A

avians
“tasselfoot” - papillomas on feet

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13
Q

Polyomaviridae
SHAPE
ENVELOPED/NON-ENVELOPED
DNA/RNA

A

icosahedral
non-enveloped
circular dsDNA
SV40 PROTOTYPE

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14
Q

Budgerigar Fledgling Disease (avian polyomavirus)
HOST
DISEASE

A

Psittacines
budges: dystrophic feathers “french molt” and systemic disease
non-budges: hepatitis, mortality

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BacT, Virology, Parasit (23 decks)

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