Important Review Flashcards

1
Q

which bacteria use a type 3 secretion system

A

STEC/EHEC
EPEC
Salmonella
Campylobacter
Yersinia

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2
Q

what bacteria is the major cause of foodborne illness in humans

A

EHEC/STEC O157:H7

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3
Q

what bacteria is the most common cause of diarrhea in farm animals “scouring”

A

ETEC

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4
Q

what bacteria is associated with severe acute necrosuppurative enteritis +/- hemorrhage

A

Salmonella

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5
Q

why should salmonella be lower on the differential diagnoses for small animals

A

not common unless on a raw diet, stray animal or sled dog

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6
Q

clinical signs of S. cholerasuis

A

host-adapted swine
acute enterocolitis, septicemia, abortion

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7
Q

1 Salmonella serovar in the US for humans

A

S. enteriditis

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8
Q

what bacteria is the cause of the most common bacterial illness in the US in humans

A

C. jejuni

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9
Q

what bacteria is a risk factor for Guillen Barre Syndrome

A

C. jejuni

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10
Q

C. jejuni pathogenesis

A

target SI & colon
translocation of the epithelium to lamina propria
zipper and trigger mechanisms
suppurative inflammation, cytokines, IL –> bloody diarrhea & necrotizing hepatitis in sheep

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11
Q

who should have C.jejuni lower on their differential list

A

old diarrhetic animals
only animals <1 yr are more susceptible

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12
Q

what bacteria is associated with acute gastroenteritis and necrotic foci on other organs

A

Yersinia

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13
Q

Brachyspira pathogenesis

A

mucous layers of LI
causes coagulative necrosis & neutrophil influx leading to diarrhea

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14
Q

Brachyspira diagnostics

A

anaerobic culture (hard)
PCR
histopathology with silver stain

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15
Q

describe Brachyspira in dogs

A

often non-pathogenic due to CLOs

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16
Q

which bacteria require normal flora to be present

A

Brachyspira
Lawsonia

17
Q

L. intracellularis clinical signs

A

acute hemorrhagic enteropathy (growers/finishers)
chronic necrotizing enteritis, adenomatosis, ileitis (weaners/growers)
garden hose gut (weaned foals)

18
Q

L. intracellularis diagnostics

A

histopathology or PCR
no culture

19
Q

what bacteria is the primary cause of infectious gastritis in humans

A

H. pylori

20
Q

what bacteria is associated with chronic lymphocytic gastritis lesions

A

H. pylori

21
Q

H. pylori patogenesis

A

colonization of gastric mucosa leading to strong inflammatory response –> gastritis in dogs/pigs

22
Q

MAP pathogenesis

A

excess pro-inflammatory cytokines causing macrophage infiltration
chronic granulomatous inflammation, thickened intestinal wall and edema

23
Q

what is the #1 contaminent of MAP

A

feces

24
Q

how is M. paratuberculosis spread to humans

A

environment
water sources

25
Q

what is MAP associated with in humans

A

Crohn’s disease

26
Q

what is the bacteria that is the most common foodborne illness

A

C. perfringens
Type A + Enterotoxin or C

27
Q

C. perfringens diagnostics

A

organism (culture or PCR toxin) + histopathological lesion

PCR of simple detection of clostridium not useful because of presence in healthy animals; neither is counting spores per high power field or ELISA

28
Q

what bacteria is the most common nosocomial infection in humans

A

C. difficile

29
Q

C. difficile pathogenesis

A

pseudomembrane formation & necrotizing colitis

30
Q

what is Tyzzer’s disease? what bacteria causes it?

A

acute necrotizing hepatitis
C. pilliforme

31
Q

what bacteria require histopathological staining with a silver stain

A

Brachyspira
C. piliforme

32
Q

what bacteria causes Braxy? what is it?

A

necrotizing abomastitis in lambs
C. septicum mainly

33
Q

what bacteria has retrograde axonal transport

A

C. tetani