Virology Flashcards

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1
Q

chickenpox and shingles are both due to what?

A

varicella zoster virus

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2
Q

chickenpox is ________ whereas shingles is ______ or ______ ______

A

chickenpox is VARICELLA whereas shingles is ZOSTER or HERPES ZOSTER

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3
Q

chickenpox:

macules to _______ to ________ to _____ to ________

A

chickenpox:

macules to PAPULES to VESICLES to SCABS to RECOVERY

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4
Q

chickenpox is severe in the extremes of ___ or if ________________

A

chickenpox is severe in the extremes of AGE or if IMMUNOCOMPROMISED

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5
Q

name a complication of chickenpox affecting the lungs

A

pneumonitis/varicella pneumonia

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6
Q

secondary to chickenpox in mother in late pregnancy is known as what?

A

neonatal VZV

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7
Q

how do you prevent neonatal VZV?

A

inject pregnant woman with immune globulin

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8
Q

shingles is seen in what distribution?

A

dermatomal distribution

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9
Q

shingles is due to ____________ of varicella zoster virus

A

shingles is due to REACTIVATION of varicella zoster virus

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10
Q

shingles is seen in which two types of people?

A

elderly and immunocompromised

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11
Q

shingles presents with ________/____ to ________ to ________ to ______

A

shingles presents with TINGLING/PAIN to ERYTHEMA to VESICLES to CRUSTS

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12
Q

shingles pain is __________ in character

A

shingles pain is NEURALGIC in character

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13
Q

shingles in the ULQ of the face is affecting which nerve?

A

ophthalmic division of the trigeminal nerve

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14
Q

shingles in the LLQ (nasal area) of the face is affecting which nerve?

A

maxillary division of the trigeminal nerve

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15
Q

shingles in the jaw of the face is affecting which nerve?

A

mandibular division of the trigeminal nerve

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16
Q

vesicles and pain in the auditory canal and throat, facial palsy and irritation of the 8th cranial nerve is known as what?

A

Ramsay-Hunt Syndrome

aka Geniculate or otic herpes zoster

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17
Q

vaccination for chickenpox is not routine in the UK for children but is in the elderly to reduce the impact of shingles.

true or false?

A

true

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18
Q

what virus is described in the following:

gingivostomatitis
pre school children
ulceration in and around mouth
lasts a week

A

herpes simplex virus

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19
Q

herpes simplex spread to eczema is known as what?

A

eczema herpeticum

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20
Q

there are 2 types of HSV: type 1 and type 2.

which is most common?

A

HVS type 1

HVS type 2 is rare

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21
Q

what is the VSV and HSV therapy?

A

aciclovir

22
Q

what is the lab confirmation of VSV or HSV?

A

viral swab

23
Q

name the condition:

fleshy, firm, umbilicated, pearlescent nodules
self limiting
common in children but can be sexually transmitted

A

molluscum contagiosum

24
Q

molluscum contagiosum treatment?

A

liquid nitrogen

25
Q

what are warts caused by?

A

HPV

26
Q

what is the treatment for warts?

A

topical salicylic acid

27
Q

warts on your feet are called what?

A

verrucas

28
Q

name the types of HPV virus in the following:

warts/verrucas -
genital warts -
cervical cancer -

A

warts/verrucas - 1 to 4
genital warts - 6 and 11
cervical cancer - 16 and 18

29
Q

vaccine used in the UK for protection against HPV cover which types of HPV?

A

6, 11, 16 and 18

30
Q

what is herpangina and what is it caused by?

A

blistering rash of back of mouth

enterovirus - not herpes virus

i.e. coxsackie

31
Q

what virus is hand, foot and mouth disease caused by?

A

coxsackie virus

32
Q

erythema infectiosum is also known as _______ _____ disease and is caused by __________ ___

A

erythema infectiosum is also known as SLAPPED CHEEK disease and is caused by PAROVIRUS B19

33
Q

how do the lab confirm the presence of parvovirus B19?

A

antibody testing - parvovirus B19 IgM test

34
Q

virus of sheep
‘scabby mouth’
firm, fleshy nodule on the hands of farmers

diagnosis?

A

Orf

35
Q

name the 3 phases of Syphilis infection

A

primary
secondary
tertiary

36
Q

what is seen at each phase of syphilis?

A

primary - ‘chancre’ painless ulcers
secondary - red rash, ‘snail track’ on mucous membrane
tertiary - CNS

37
Q

what bacterium causes syphilis?

A

Treponema pallidum

38
Q

syphilis treatment?

A

penicillin

39
Q

name the vector in Lyme disease

A

tick

40
Q

is the cause of Lyme disease bacterial or viral?

A

bacterial

41
Q

name the early and late presentations of Lyme disease

A

early - erythema migrans

late - heart block, nerve palsies and arthritis

42
Q

Lyme disease therapy?

A

doxycycline or amoxicillin

43
Q

1 in _ people infected with Zika virus become ill

A

1 in 5 people infected with Zika virus become ill

44
Q

timescales for symptom onset and resolution of Zika virus?

onset -
resolution -

A

timescales for symptom onset and resolution of Zika virus?

onset - 3-12 days
resolution - 2-7 days

45
Q

symptoms of Zika virus (3)

A

mild fever
rash
headaches

46
Q

presentation of Zika virus is similar to ______ and ____________

A

presentation of Zika virus is similar to DENGUE and CHIKUNGUNYA

47
Q

Zika virus is spread by what?

A

mosquito Aedes Aegypti

48
Q

Zika virus is a ______ disease requiring ________________

A

Zika virus is a SEVERE disease requiring HOSPITILIZATION -

49
Q

____________ and ________ _____ syndrome are complications of zika virus

A

MICROCEPHALY and GUILLAIN BARRE syndrome are complications of zika virus

50
Q

monkeypox is very ____

A

monkeypox is very RARE