Pathology - Rash Flashcards
the dermis is composed of which 2 types of collagen?
type 1
type 111
name the pathological terms to describe the following:
- increased thickness of keratin layer
- persistence of nuclei in the keratin layer
- increased thickness of epithelium
- increased thickness of keratin layer - HYPERKERATOSIS
- persistence of nuclei in the keratin layer - PARAKERATOSIS
- increased thickness of epithelium - ACANTHOSIS
irregular epithelial thickening is also known as ______________
irregular epithelial thickening is also known as PAPILLOMATOSIS
oedema fluid between the squames increases the prominence of intercellular prickles describes what?
spongiosis
how many classifications of reaction pattern are there?
4
name the 4 main reaction patterns
- spongiotic-intraepidermal oedema
- psoriasiform-elongation of the rete ridges
- Lichenoid-basal layer damage
- vesiculobullous-blistering
name a disease/condition the is classifies as spongiotic-intraepidermal oedema
eczema
name a disease/condition the is classifies as psoriasiform-elongation of the rete ridges
psoriasis
name a disease/condition the is classifies as Lichenoid-basal layer damage
lichen plants and lupus
name a disease/condition the is classifies as vesiculobullous-blistering
pemphigoid, pemphigus and dermatitis herpetiformis
psoriasis is associated with epidermal ___________ and specific ___ types
psoriasis is associated with epidermal HYPERPASIA and specific HLA types
Lichen planus histology:
- irregular ________ acanthosis
- ______granulosis and ortho______________
- upper dermal _________ infiltrate
- basal damage with ______ ____ formation
Lichen planus histology:
- irregular SAWTOOTH acanthosis
- HYPERgranulosis and orthoHYPERKERATOSIS
- upper dermal LYMPHOCYTE infiltrate
- basal damage with CYTOID BODY formation
_______ lupus resembles lichen planus
DISCOID lupus resembles lichen planus
what is the primary feature in immunobullous diseases?
blisters
name 3 important immunobullous disorders
- pemphigus
- bullous pemphigoid
- dermatitis herpetiformis