Virology Flashcards
Are DNA viruses double or single stranded and what is the exception
All are double stranded DNA - except Parvoviridae
What DNA viruses are circular and which are linear
All are linear, except Papilloma, Polyoma, and Hepadna, which are circular
What is the genomic structure of RNA viral genome
All RNA viruses are single stranded RNA except Reoviridae
What RNA viruses are positive stranded
Retrovirus Togavirus Flavivirus Coronavirus Hepevirus Calicivirus Picornavirus (Retro toga party where I drank flavored coronas and ate hippy california pickles)
What is the difference between positive and negative stranded RNA
Positive strand = like mRNA and can translate directly
Negative strand = must transcribe before translating
What naked viral genomes are infectious?
Most dsDNA viruses (except pox and HBV)
Positive stranded ssRNA (=mRNA)
What naked viral genomes are not infectious
Negative strand ssRNA
dsRNA
They require polymerases that are part of a complete virion
Where do DNA viruses replicate, and what is the exception
All replicate in nucleus except poxvirus
Where do RNA viruses replicate and what is the exception
All replicate in cytoplasm except influenza and retrovirus
What are the naked viruses?
Papilloma Adeno Parvo Polyoma Calici Picorna Reo Hepe (Give PAPP smears and CPR to a naked Heppy) DNA = PAPP; RNA = CPR and hepe
Where does herpesvirus get its envelope
Unlike other enveloped viruses that get their envelope from plasma membrane when exiting, herpesvirus gets its from the nuclear membrane
Which DNA viruses are naked
PAPP Papilloma Adeno Parvo Polyoma
Which RNA viruses are naked
CPR + hippy Calici Picorna Reo Hepe
Where does Pox virus replicate
Pox is the only DNA virus not to replicate in the nucleus - it replicates in the cytoplasm because has own DNA-dependent RNA polymerase
What is the structure of Pox virus
Unlike all other DNA viruses that are icosahedral, pox has a complex structure
What are the DNA viruses?
They are HHAPPPPY viruses: Hepadna Herpes Adeno Pox Parvo Papilloma Polyoma
Name all of the herpesviruses
HSV-1, HSV-2, VZV, EBV, CMV HHV-6 (Roseola), HHV-7, HHV-8 (Kaposi)
What is the structure of all herpes viruses
Enveloped, DS and linear
What medical condition does hepadnavirus cause
HBV
What is the structure of hepadna virus
Partially DS and circular
What virus is not a retrovirus but contains reverse transcriptase
HBV-hepadnavirus
What is the structure of adenovirus
DNA virus, nonenveloped, DS and linear
What medical conditions does adenovirus cause
Febrile pharyngitis
Acute hemorrhagic cystitis
Pneumonia
Conjuntivitis
What is the structure of parvovirus
DNA virus, naked and SS (only DNA virus that is SS), linear (-)
