VIROLOGY

Question 1

DNA VIRUS

all are DS-DNA except -
all are LINEAR except -
all are ICOSAHEDRA except -
all are NAKED except -
all Replicate in NUCLEUS except -

Answer 1

PARVO
PAPOVA / HEPADNA
POX
HHP - HERPES, HEPADNA, POX enveloped
POX cytoplasm

Question 2

RNA VIRUS

all are SS-RNA except
all are ENVELOPED except PCR
Generally HELICAL except CPT-FRR
all Replicate in CYTOPLASM except

Answer 2

RED
PICORNA, CALICI, REO
CALICI, PICORNA, TOGA, FLAVI, REO, RETRO
RETRO, ORTHOMYXO nucleus

Question 3

DNA VIRUSES

Causes ACUTE RESPIRATORY DISTRESS
Epidemic keratoconjunctivitis

Produces GRAPE -LIKE CPE
Hematologic finding: SMUDGE CELLS

Answer 3

ADENOVIRUS

Question 4

DNA VIRUS

HBV (Hepatitis B Virus)

Causes Hepatitis B
Transmitted parenteral (blood to blood transmission)
Infectious particle: DANE Particle
Hepa B with carrier state

Answer 4

HEPADNA VIRIDAE

Question 5

DNA VIRUS

B19 virus

Infects erythroid (IMMATURE RBC) precursors: normoblast, pronormoblast
Causes transient aplastic anemia crisis
Causes 5th disease - erythema infectiosum
Characterized by SLAPPED CHEEK RASH or LACY PATTERN OF ERYTHEMA
Causes Hydrops fetalis
Causes PPGSS (Popular Purpuric Gloves & Socks Syndrome)

Answer 5

PARVOVIRIDAE

Question 6

DNA VIRUS

HPV (Several strains)

Causes genital or skin warts
HPV 16 & 18 implicated in cervical cancer cases
Observation of KOILOCYTES in PAPS-STAINED smears

Answer 6

PAPILLOMAVIRIDAE

Question 7

DNA VIRUS

Regarded as the LARGEST
With BRICK shaped virion
With COMPLEX capsid symmetry

Variola virus / Orthopox virus: SMALLPOX (vax used for eradication is form vaccination)
A virulent form of Variola virus, vaccine source: VACCINIA VIRUS
Alastrim virus: VARIOLA MINOR (mild form of smallpox)
Molluscum contagiosum virus: MOLLUSCUM a.k.a. water warts

Orf virus - transmitted thru direct contact with sheep in which nodules in hands may be seen
Monkey Pox virus - latest outbreak reported by WHO in 2022, MOT: Close contact
Cowpox virus

Answer 7

POXVIRIDAE

Question 8

DNA VIRUS

• causes multifocal leukoencephalopathy
  Specimen for detection:
  (+)
• causes: Hemorrhagic cystitis
  Specimen for diagnosis:
  (+)
• merkell cell carcinoma

Answer 8

POLYOMAVIRIDAE

JC virus
CSF
BIZZARE ASTROCYTES

BK virus
URINE
DECOY CELLS

MC virus