Virology

Question 1

cytopathic effect

Answer 1

cell damage from virus

Question 2

Virion

Answer 2

ss nucleic acid with capsid protein coat

Question 3

Nucleotide reverse transcriptase inhibitors

Answer 3

DNA blocked with primer

Question 4

AZT

Answer 4

prevent synthesis by binding to base stopping chain

Question 5

Antiviral agents

Answer 5

formaldehyde, metals, lipids, UV, phenol/halogen, heat

Question 6

Replication

Answer 6

adsorption/attachment, penetration, uncoating, synthesis, assembly, release

Question 7

transformation

Answer 7

cell get fucked up, oncovirus (HIV/HPV)

Question 8

inclusion

Answer 8

Negri body (rabies in neuron), Cowdry body (HSV/VZV)

Question 9

syncytium

Answer 9

giant multinucleated cell, RSV/HIV/rubeola

Question 10

Virus culture

Answer 10

tube (2 week)/shell viral (coverslip, centrifuge, incubate 24 hr, monoclonal ab stain), gas exchange, inverted scope

Question 11

Bacteriophage

Answer 11

transduction, phage synthesis + host DNA, into new host (lyophilized, hydrogel, dry particle, encapsulate in liposomes)

Question 12

Giruses

Answer 12

Nucleocytoviricota, chimera

Question 13

Viroid

Answer 13

infectious circular ssRNA nucleic acids, catalytic capability, no capsid, Hep D

Question 14

Bdellovibrio spp.

Answer 14

GN aerobe, feed on GN protein/nucleic acid

Question 15

Prion

Answer 15

bovine/transmissible spongiform encephalopathy, sheep scrabie, Creutzfeldt-Jokab disease, 900F for 4 hrs

Question 16

Influenza A

Answer 16

surface glycoprotein: hemagglutinin (H) binds to host detected by antisera, Neuraminidase (N) cleaves budding virus, 8 ssRNA

Question 17

flu C

Answer 17

no N protein gene, genetically stable, 7 ssRNA

Question 18

Respiratory syncytial virus (RSV)

Answer 18

croup, infants/young children, bronchiolitis

Question 19

SARS-Cov

Answer 19

Glycoprotein S in virus envelope/ACE2 receptor enter host, cytokine storm

Question 20

Extracorporeal membrane oxygenation (ECMO)

Answer 20

3-10 day cervical artery and vein bypass

Question 21

NW Hantavirus

Answer 21

Hantavirus pulmonary syndrome, lung fail

Question 22

Sin Nombre Hantavirus

Answer 22

not transmissible, deer/white footed mouse

Question 23

Cytomegalovirus

Answer 23

congenital, enlarge infected cells, buffy coat isolation

Question 24

1. Rubella

Answer 24

German measles, rash (not raised), lymphadenopathy

Question 25

2. Rubeola

Answer 25

measles, cold (prodromal period) to Koplik spots (inside cheek) to maculopapular rash (flat and bumpy)

Question 26

3. Mumps

Answer 26

paramyxovirus, parotid gland, amylase

Question 27

4. Variola

Answer 27

synchronous rash

Question 28

Filovirus

Answer 28

Marburg (monkey/bat), Ebola (bushmeat)

Question 29

Lassa virus - Hemorrhagic

Answer 29

Mastomys genus mice, nonspecific symptoms to pleural effusion

Question 30

West Nile virus

Answer 30

CNS, neurodegenerative like, mosquito/bird

Question 31

Dengue virus

Answer 31

dengue hemorrhagic fever DHF, 2 serotype exposed