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Fall 2024 > Leukemias > Flashcards

Leukemias Flashcards

1
Q

Type I Blasts

A

Myeloblasts/unclassifiable cells, no granules

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2
Q

Type II Blasts

A

<20 granules, N:C lower

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3
Q

Type III Blasts

A

> 20 granules

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4
Q

Nonerythroid nucleated cells (NEC)

A

Blasts

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5
Q

M0 AML

A

min dif, <3% SBB+, heterogeneous, no auer rods, TdT+

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6
Q

M1 AML

A

myelo, no maturation (15-20%)

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7
Q

M2 AML

A

myelo, mature (25-30%), t(8;21)(q22;q22)(AML1/ETO)

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8
Q

M3 APL

A

Young patients, ATRA, DIC, Promyelocytic, hypergranular (10-15%), t(15;17)(q22;q12)(PML/RARa)

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9
Q

M4 AMML, NSE, CAE

A

Myelomonocytic (20-30%), gums,

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10
Q

M4eo AMML

A

inv(16)(p13;q22) or t(16;16)(p13;22)(CBFB/MYH11)

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11
Q

M5a AMol, NSE+, MPO/SBB=

A

monoblastic, no maturation, 11q23 (MLL), gums

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12
Q

M5b AMol

A

monoblastic, matureM

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13
Q

M6 AEL, PAS+

A

erythroleukemia

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14
Q

M7 AMkL, CD41, 61, 42

A

megakaryoblastic

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15
Q

acute panmyelosis with myelofibrosis

A

AMkL w IMF

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16
Q

HLA-DR +

A

AML, B lymph

17
Q

CD13, CD33 +

18
Q

CD19, CD20, CD22 +

19
Q

CD10 +

A

B or T lymph(= for some reason too)

20
Q

CD2, CD3, CD5, CD7 +

21
Q

De novo, mulitlineage dysplasia

A

following MDS/MDN, >50% of cells

22
Q

ALL

A

SBB MPO CAE NSE =, PAS +

23
Q

PreB ALL L1

A

homo, CD13, CD33

24
Q

Common ALL

25
Pro-B ALL
26
B-cell ALL
27
T-Cell ALL L2
28
Null cell ALL
29
L1
small blasts, homo, scant cyto, no nucleoli
30
L2
hetero, more cyto, nucleoli,
31
L3 Burkitt's type
large blasts, basophilic abundant cyto and vacuoles
32
TdT+
L1, L2
33
CALLA=
L3
34
CALL+
PreBCell ALL (L1)

Fall 2024 (14 decks)

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