Leukemias Flashcards

1
Q

Type I Blasts

A

Myeloblasts/unclassifiable cells, no granules

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2
Q

Type II Blasts

A

<20 granules, N:C lower

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3
Q

Type III Blasts

A

> 20 granules

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4
Q

Nonerythroid nucleated cells (NEC)

A

Blasts

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5
Q

M0 AML

A

min dif, <3% SBB+, heterogeneous, no auer rods, TdT+

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6
Q

M1 AML

A

myelo, no maturation (15-20%)

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7
Q

M2 AML

A

myelo, mature (25-30%), t(8;21)(q22;q22)(AML1/ETO)

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8
Q

M3 APL

A

Young patients, ATRA, DIC, Promyelocytic, hypergranular (10-15%), t(15;17)(q22;q12)(PML/RARa)

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9
Q

M4 AMML, NSE, CAE

A

Myelomonocytic (20-30%), gums,

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10
Q

M4eo AMML

A

inv(16)(p13;q22) or t(16;16)(p13;22)(CBFB/MYH11)

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11
Q

M5a AMol, NSE+, MPO/SBB=

A

monoblastic, no maturation, 11q23 (MLL), gums

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12
Q

M5b AMol

A

monoblastic, matureM

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13
Q

M6 AEL, PAS+

A

erythroleukemia

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14
Q

M7 AMkL, CD41, 61, 42

A

megakaryoblastic

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15
Q

acute panmyelosis with myelofibrosis

A

AMkL w IMF

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16
Q

HLA-DR +

A

AML, B lymph

17
Q

CD13, CD33 +

A

AML

18
Q

CD19, CD20, CD22 +

A

B lymph

19
Q

CD10 +

A

B or T lymph(= for some reason too)

20
Q

CD2, CD3, CD5, CD7 +

A

T lymph

21
Q

De novo, mulitlineage dysplasia

A

following MDS/MDN, >50% of cells

22
Q

ALL

A

SBB MPO CAE NSE =, PAS +

23
Q

PreB ALL L1

A

homo, CD13, CD33

24
Q

Common ALL

A
25
Q

Pro-B ALL

A
26
Q

B-cell ALL

A
27
Q

T-Cell ALL L2

A
28
Q

Null cell ALL

A
29
Q

L1

A

small blasts, homo, scant cyto, no nucleoli

30
Q

L2

A

hetero, more cyto, nucleoli,

31
Q

L3 Burkitt’s type

A

large blasts, basophilic abundant cyto and vacuoles

32
Q

TdT+

A

L1, L2

33
Q

CALLA=

A

L3

34
Q

CALL+

A

PreBCell ALL (L1)