Viral Structure

Question 1

Influenza attachment

Answer 1

Viral protein: Hemagglutinin (HA)

Cell surface molecules: Sialic acid oligosaccharides

Question 2

HIV attachment

Answer 2

Viral protein: gp120

Cell surface molecules: CD4, CXCR4, CCR5

Question 3

Herpesviruses type of latency

Answer 3

Episomal latency

Question 4

HIV type of latency

Answer 4

Proviral latency

Question 5

Tenofovir

Answer 5

Blocks HIV reverse transcriptase and hepatitis B viral polymerase

Question 6

Remdesivir

Answer 6

Blocks viral RNA-dependent RNA polymerase of SARS-CoV-2

Question 7

Dolutegravir

Answer 7

Blocks integration of HIV into host DNA

Question 8

DNA versus RNA viruses (ds versus ss, location of replication)

Answer 8

DNA viruses: ds DNA (except parvovirus), replicate in nucleus (except poxvirus)
RNA viruses: ss RNA (except rotavirus), replicate in cytoplasm (except influenza virus and retroviruses)