Viral Infections Flashcards
Characteristics of infectious mononucleosis?
Pharyngitis
Generalised lymphadenopathy
Hepatosplenomegaly
Lymphadenitis in EBV infection most commonly affects which lymph nodes?
Posterior cervical chain
Most common causes of secondarily infected chickenpox?
Group A strep
Staph aureas
Causative agent for Roseola Infantum (Sixth disease)?
HHV6 (Human herpes virus type 6)
HHV-8 is strongly associated with what disease process?
Kaposi sarcoma
Parvovirus B-19 is the causative agent of which disease process?
Erythema infectiosum (slapped cheek, fifth disease)
Disease processes associated with EBV infection include? (10)
Stevens Johnson Syndrome Hepatitis Herpes Infectious Mononucleosis (glandular fever) Alice in Wonderland syndrome Non-hodgkin's lymphoma Hodgkin's disease Post-transplant lymphoproliferative disorder Nasopharyngeal carcinoma Herpangina
Incubation period of chickenpox?
11 - 21 days
Most common cause of SJS?
Herpes simplex virus
Other causes include drugs - sulphonamides, phenytoin, penicillins, EBV infection
What type of virus are the herpes virus family?
Encapsulated Double Stranded DNA virus
Which 2 Herpes viruses are associated with malignancy?
EBV
HHV8 (Kaposi’s Sarcoma)
Where is the viral reservoir for EBV infection?
B cells
Malignant associations with EBV include what? (4)
NHL (Burkitt’s + primary cerebal lymphoma)
Hodgkin’s disease
Post transplant lymphoproliferative disease
Nasopharyngeal carcinoma
Which of the hepatitis viruses are RNA viruses?
And which one of the hepatitis viruses is a DNA virus?
Hepatitis A, C, D, E are all RNA viruses
Hepatitis B is a DNA virus
EEG findings associated with HSV encephalitis?
Periodic lateralised epileptiform discharges
