Antibiotics/antiviral medications

Question 1

Site of action of Glycopeptides/B-lactams?

Answer 1

Cell wall

Question 2

Site of action of macrolides and chloramphenicol?

Answer 2

Protein synthesis (Ribosomes)

Question 3

Site of action of Quinolones/Rifampicin/Sulphonamides?

Answer 3

All act on DNA replication

Question 4

Which Abx can be used in the treatment of MRSA?

Answer 4

Vancomycin

Linezolid

Question 5

Which Abx are Extended Spectrum B Lactamase (ESBL) still sensitive to?

Answer 5

Meropenem/Imipenem

Question 6

Which antibiotic is Listeria sensitive to?

Answer 6

Ampicillin

Question 7

Which antibiotic causes “Red man syndrome”?

What is the cause of this reaction?

Answer 7

Vancomycin
Histamine release (slow the rate of infusion)

Question 8

Estimated cross-sensitivity to cephalosporins with penicillin allergy?

Answer 8

~10%

Question 9

What is Ethambutol used against?

Answer 9

Mycobacterium TB

Other mycobacteria

Question 10

Main SE of Ethambutol?

Answer 10

Optic neuritis
(visual acuity and colour vision should be checked prior to commencement)
Should not be used in <6yrs because difficult to assess colour vision

Question 11

Side of effects of Isoniazid?

Answer 11

Hepatitis
Peripheral neuropathy
Neuritis

Question 12

SE of amoxicillin/augmentin?

Answer 12

Diarrhoea

hepatotoxicity