Viral Hepatitis Flashcards
Types of hepatitis virus
Hepatitis (A,B,C,D,E)
Which one of hepatitis virusis is Rna virus and which is a Dna virus
.All of them are RNA viruses EXCEPT
(Hepatitis B is Douple strand DNA)
Mode of transimision of hepatitis A virus
Feco-oral / IP 2-6 wks
Mode of transmition of hepatitis B virus
Parental transmission
Piercing instrument like needles
Transfusion of contaminating blood
Sexual transmission
Mode of transmission of hepatitis c virus
Parental
Sexual or pernatal route
Ip 7 wks
Mode of transmission of hepatitis D virus
Parental
Mode of transmission of Hepatitis E virus
Enteric Feco-oral
Which types of hepatitis known as acute disease and why
Hepatitis A , E due to Food poisioning
Other types are chronic
What dose hepatitis A known for
Known as Epidemic Jaundice
(Most common type of jaundice)
Reservoir host of hepatitis A
Man is the only reservoir
Period of communicabillity of hepatitis A
Person is infective to others
( 2 wks before and 2 wks after the onsent of jaundice )
How can we destroy hepatitis A
Agent resist heating but it can be inactivated by boiling for 5 minutes or autoclaving
In Hepatitis A The ratio of subclinic to clinic infection is
12:1
Labratory diagnosis of hepatitis A
By Elisa to
1.demonstrate specific #Ig-M antibody((which persist for short period after apperance of jaundice))
2.detect specific #Ig-G anti body which increase steadily
Prevention and control of hepatitis A
1.notification of diagnosed cases
2.compelete bed rest ,symptomayic managment of the cases
3.Good sanitation , personal hygiene
4.disinfection by use of 0.5% Nat hypochloride
5.healt education to Food handlers
6.immunoglobulin for pre , post exposure prophylaxis
7.vaccination (given 2 doses )
Immunity for hepatitis A
Immunity after infection is life long
What dose Hepatitis B known for
It known as serum hepatitis or long incupation period hepatitis
IP(( 2-6 MONTHS ))
Hepatitis b is
Douple stranded DNA viruse
HBs Ag (hepatitis B infective antigen importance
First serologucal marker appear in blood (most helpful labratory methid for diagnosis)
Anti hepatitis B core antibody “anti HBC” importance
IgM indicate recent infection
IgG indicate past infection
Anti HBs importance
Indicate immunity either from vaccination or resolved natural infection
Anti HBe importance
Indicate lower level of infectivity
HBv carrier is
Any person have remaining HBsAg +ve for more than 6 months
Prevention , control of hepatitis B virus
1.pre and post exposure prophylaxis with immunoglobulins and engerix B vaccine
2.active immunization (vaccine) given to all new born babies , high risk group
3.universal screening of blood for HBsAg
4.use of clean surgical instrument and disposable heamodialysis equipment
Which have higher chance to develop a carrier state in hepatitis B virus case adult or infant
Infant have 50% chance
Childhood to adult 5-10%
How to destroy hepatitis B virus
It destroyed by sodium hypochlorite or autoclave for 30 minut
Most common areas known foe hepatitis C virus is
Africa and east asia
Sofosbuvir (sovaldi) given as cure for
Hepatitis C virus
Other names for hepatitis D
Delta hepatitis
What hepatitis D need hepatitis B for
Require hepatitis B for it is replication
How to prevent hepatitis D
Can be prevented by hepatitis B vaccine
(No antiviral treatment for hepatitis D)
