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Alimentary System > Viral Hepatitis > Flashcards

Viral Hepatitis Flashcards

1
Q

What forms of viral hepatitis are enteric?

A

HAV
HEV
Cause acute infections

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2
Q

What forms of viral hepatitis are parenteral?

A

HBV
HCV
HDV
Cause chronic disease

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3
Q

What kind of virus is each form of hepatitis?

A

A- RNA
B- DNA
C- RNA
D- Incomplete RNA
E- RNA

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4
Q

How does Hepatitis A spread?

A

Faecal- oral
Shellfish

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5
Q

What groups receive the HAV vaccine?

A
  • Travellers
  • CLD patients
  • Haemophiliacs
  • Occupational exposure- la workers
  • Men who have sex with men (MSM)
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6
Q

How does Hepatitis B spread?

A

Blood
IV drug users
Sexual
Direct contact

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7
Q

What are the types of HBV antigens?

A

HBsAg (surface antigen): presence of virus
HBeAg (e antigen): active replication
HBcAg (core antigen): active replication
HBV DNA: active replication

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8
Q

What are the types of HBV antibodies?

A

HBc IgM: acute
HBc IgG: chronic
Anti HBe: inactive virus

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9
Q

What does the following indicate?
HBsAG +ve
Anti HBs -ve
Anti HBc IgG +ve

A

Chronic infection

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10
Q

What does the following indicate?
HBsAG -ve
Anti HBs +ve
Anti HBc IgG +ve

A

Past infection

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11
Q

What does the following indicate?
HBsAG +ve
Anti HBs -ve
Anti HBc IgM +ve

A

Acute infection

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12
Q

What does the following indicate?
HBsAg -ve
Anti HBs -ve
Anti HBc -ve

A

No previous exposure to HBV or vaccine

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13
Q

What does the following indicate?
HBsAg -ve
Anti HBs +ve
Anti HBc -ve

A

Hep B vaccination

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14
Q

What does HBc IgM indicate?

A

Acute infection

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15
Q

What does HBc IgG indicate?

A

Chronic infection

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16
Q

What is the aim of HBV treatment?

A

To clear HBsAg and prevent cirrhosis and HCC (hepatocellular carcinoma)

17
Q

How is Hepatitis C spread?

A

Blood transfusion
IV drug users
Sexual content

18
Q

What is the pathology of HCV?

A

Early infection is often mild/asymptomatic
85% develops silent chronic infection
25% develop cirrhosis
4% develop HCC

19
Q

What is HDV?

A

Parasite of HBV- needs HBV for its assembly
Co-infection or super infection with HBV
5% of HBV carriers have HDV co-infection

20
Q

What is the treatment for HEV?

A

No specific treatment

21
Q

What are the other infective causes of hepatitis?

A

Hepatitis F
Hepatitis G
EBV
CMV
Herpes simplex
Malaria
Syphilis
Yellow fever

Alimentary System (24 decks)

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