Gastric Cancer Flashcards
What are the majority of gastric cancers?
Adenocarcinomas
What are some other gastric tumours?
GIST
MALT
What are the risk factors for gastric cancer?
Pernicious anaemia
H. pylori
Atrophic gastritis
Lower social class
Smoking
Diet
Genetics
What are the symptoms of gastric cancer?
Dyspepsia
Satiety
Nausea
Vomiting
Dysphagia
Anaemia
Weight loss
What tests are used to diagnose gastric cancer?
Gastroscopy + multiple ulcer edge biopsies
EUS- depth of invasion
CT/MRI- staging
Laparoscopic- staging of locally advanced tumours
What are the surgical treatments for gastric cancer?
Endoscopic resection- early gastric cancer
Partial gastrectomy- advanced distal tumour
Total gastrectomy- advanced proximal tumour
What is Roux-en-Y reconstruction?
Following total gastrectomy, the proximal duodenal stump is over sewn.
The proximal jejunum is divided from the distal duodenum and connects with the oesophagus.
The distal duodenum is connected to the distal jejunum
What are the non surgical treatments for gastric cancer?
Combination chemotherapy
Targeted therapies