Viral Diseases of Dogs I (8) Flashcards

1
Q

What has the most clinical importance for dog viruses?

A

canine parvovirus infection

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2
Q

What is characteristic of herpesvirus?

A

latent infection, with recrudescence and intermittent or continuous virus shedding

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3
Q

Herpesvirus is [enveloped/unenveloped]

A

enveloped

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4
Q

Herpesvirus is [stable/unstable] in environment

A

unstable - which is why it spreads by close contact

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5
Q

Is Herpesvirus species specific?

A

yes - some exceptions

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6
Q

What is the epidemiology of Herpesvirus?

A

present worldwide in domestic and wild dogs
seropositive rates of >30% are common in field dogs

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7
Q

T/F: Pups can’t be born without the development of disease of herpesvirus

A

FALSE - maternal antibodies through passive transfer to puppies doesn’t always happen

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8
Q

What kinds of infection is Herpesvirus in dogs?

A

respiratory infection - mild runny nose or cough
reproductive infection - vesicles or postures of genitalia

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9
Q

Most adult infections of Herpesvirus is [symptomatic/asymptomatic]

A

asymptomatic

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10
Q

Puppies _____ age are at the highest rate of contracting Herpesvirus

A

1-3 weeks

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11
Q

For Herpesvirus, the mortality rate is high among puppies exposed during _____ and the first week of life

A

whelping
disease progression is rapid
most puppies die within 24 to 48 hours after onset of clinical signs

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12
Q

In puppies, Herpesvirus is called

A

fading puppy syndrome - systemic disease

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13
Q

What is the preferred diagnostic tools for Herpesvirus?

A

PCR
serology + clinical sigtns
virus culture
necropsy

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14
Q

What is Canine Infectious Respiratory Disease Complex?

A

bordetella bronchiseptica
canine parainfluenza virus
canine distemper
canine infleunza
canine herpesvirus
serotype 2 of canine adenovirus

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15
Q

What is the treatment for herpesvirus for puppies?

A

heat lamp, pad
IV fluids
prognosis is poor

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16
Q

What is the prevention for herpesvirus for puppies?

A

no vaccine

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17
Q

What is pseudorabies in dogs?

A

porcine herpesvirus 1
uncommon in domestic dogs

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18
Q

What are clinical signs of pseudorabies in dogs?

A

frenzy associated with intense pruritus
paralysis of jaws and pharynx
howling
death

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19
Q

What are other characteristics of adenovirus?

A

virus resistant in environment
wife range of clinical presentations
confirmed bye virus isolation or PCR
direct contact transmission or aerosol
usually more poultry than mammals

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20
Q

For adenovirus 1, infectious canine hepatitis is rarely seen in the USA in domestic dogs, except in ______

A

shelter situations

21
Q

What is this a symptom of?

A

infectious canine hepatitis - adenovirus 1
“blue eye”

22
Q

How is infectious canine hepatitis transmitted?

A

in bodily secretions, especially urine
travels to the tonsils and regional lymph nodes where it replicates
then travels to liver where it replicates again

23
Q

What are the presenting signs of CAV2 infection?

A

respiratory: dry, hacking cough, loss of appetite
can get this in crowded conditions

24
Q

What is the treatment and prevention for CAV1 and CAV2?

A

let virus run course if healthy
affected dogs should be isolated
vaccination is recommended

25
Where does papillomavirus generally appear?
occurs principally in the mouth offensive breath - can be very florid
26
Which virus indicates a measure of immune function?
canine warts (papillomavirus)
27
If the immune system reacts with papillomavirus, it can be what kind of infection
acute self-limiting
28
The oral antibiotic _____ is sometimes used to treat papillomavirus
azithromycin
29
What is the properties of papillomavirus?
small naked capsid, DNA genome
30
How is papillomavirus acquired? Infects?
by close contact infects the epithelial cells of the skin of mucus membrane
31
For the papillomavirus, virus persists in the _____ layer and then produces virus in thermally differentiated _______
basal layer keratinocytes
32
Parvovirus replicates only in _____
dividing cells
33
What viruses can cause abortion or fetal abnormalities (a virus we've talked about thus far)
parvovirus
34
How does a dog contract parvovirus?
transmission by contact or fomites
35
Canine parvovirus is an example of antigenic [shift/drift]
drift
36
What is the name for canine parvovirus?
CPV-2b
37
Parvovirus is primarily transmitted by ______ route
fecal-oral
38
In parvovirus, the virus is [stable/unstable] in the environment
stable (that's why it lives in the ground so long)
39
Where is parvovirus derived?
came from cats - usually stays 2a in cats
40
What is the pathogenesis for parvovirus?
initial replication in tonsils in lymph nodes disseminated in blood (viremia) attacks crypt cells, leads to loss of epithelium in small intestine
41
Why is parvovirus so contagious?
infects all ages puppies between weening and 6 months of age most susceptible
42
Parvovirus presents primarily as a(n) _______ disease
acute enteric disease
43
Which type of vaccine is parvovirus?
modified live vaccine (attenuated)
44
Are there parvovirus treatments?
not tamiflu interferon omega hyperimmune serum - though not widely available
45
What are characteristics of coronavirus and torovirus in dogs?
virus unstable in environment many serotypes transmission by aerosol, direct contact, fomites, and common vehicl
46
What is the pathogenesis for canine coronavirus?
confined in intestines upper 2/3rds of small intestine confined in intestines
47
How is canine coronavirus transmissited?
fecal-oral route, through contaminated fomites crowding and unsanitary conditions
48
Which is characteristic of loose stool and a **fetid** odor and orange tint?
canine coronavirus