Vetan Topic 2 and 4 Flashcards
What are the five processes that take place during early developmental stages?
- growth
- morphogenesis
- patterning
- cytodifferentiation
- tissue interaction
It refers to the increase in the number or size of cells that results in the increase in mass of the organism.
growth
Process which refers to the entire group of processes that mold the external & internal
configuration of the embryo. This involves a change in the shape or location or even
death of a cell or tissue.
morphogenesis
elongation of epithelial cells. Ex. elongation of epiblasts during gastrulation.
epithelial expansion
programmed degeneration & eventual death of
cells in areas called necrotic zones
normal cell death or apoptosis
outward folding or outpocketing of the epithelium. Ex. development of optic vesicle from neural tube
evagination
downward migration of epithelium with secondary, tertiary branches given off from the main branch. Ex. development of lung and duct system
of major salivary glands.
budding and branching
separation of an invaginated epithelium from the original epithelium; the second stage in more complex morphogenetic reorganization. Ex.
formation of neural tube
vesicle formation
infolding or depression of epithelium to form a pit or groove; often the first stage in more complex morphogenetic reorganization. Ex. formation of neural tube
invagination
focal thickening of surface ectoderm, often in response to an underlying mesenchymal aggregation
placode formation
grouping of mesenchymal cells to form a densely
packed subpopulation within a mesenchymal tissue. Ex. formation of enamel organ
and vertebra.
mesenchymal aggregation
migration of epithelial cells to the underlying area to form mesenchymal cells. Ex. formation of mesoderm
delamination
is the establishment of invisible blueprint of cell
subpopulations that serves as a guide in the formation of a particular tissue or organ
patterning
complex tortuous process by which each cell or cell line attains and expresses a stable phenotype or a process by which a cell becomes specialized
and the final product is a differentiated cell
cytodifferentiation
is a process in which the presence of one tissue
or structure induces or causes the development of another tissue or structure
tissue interaction or tissue induction
period or the time during which each organ system in the body is being formed and obligatory inductive tissue interactions and morphogenesis are occurring
critical period
genes that cause congenital defects
deleterious genes
Causes of congenital malformation or defect?
- Hereditary or genetic factors
- Environmental factors