LN 05 (Healing Process) Flashcards
restores the tissue architecture back to its shape,
and reinstate functions back to normal
Healing process
2 process of healing
- healing by repair
- healing by regeneration
occur at sites where there is only minimal loss of tissue, inflammation is moderate, and the tissue defect is closely apposed such as a cut or surgical wound
healing by first intention
type of healing in which that there is considerable loss of tissue edges are separated by a space or defect necessitating a large bulk of reparative tissue to fill the gap
Healing by second intention
In series of events of secondary union, the tissue that fill-in the gap is called ______ tissue and is beneath the coagula
granulation
type of repair is typified by what happens in the
lungs
repair by resolution
In cases where there is incomplete resolution of inflammation
repair by organization
implies that lost cells are replaced by cells of the same kind
regeneration
species that lost most of their capacity
to regenerate total body structures
mammals/mammalian species
continue to multiply throughout life to replace
those shed or destroyed by normal physiological processes
labile cells
exfoliate throughout life and are being replaced every few days
labile cells
retain their latent capacity to regenerate, but do not actively replicate under normal circumstances
stable cells
Stable cells are present in?
- Parenchymal cells of glands
- Mesenchymal cells
these cells cannot regenerate and therefore damage to these cells represents permanent loss
Permanent cells
Give three permanent cells
- neurons
- skeletal
- cardiac muscle
accumulation of excessive amounts of collagen giving rise to a protruding tumor-like scar
keloid
excessive formation of granulation tissues that protrudes above the level of injury
exuberant granulation or proudflesh
Factors Influencing Healing
- Tissues involved
- Vascularity
- Protective covering
- Nutrition
- Hormones
- Age
- Magnitude of injury
- Presence of infection
- Presence of nerve supply
necessary for healing for they regulate metabolic activities
thyroid hormones
delays healing for they interfere with
the maturation of collagen and in the on-going inflammatory process
corticosteroid
essential for the healing process
for they involved in polymerization and thus maturation of collagen
Vit. C and D
Avascular areas that do not heal
- neck of femur
- ulna
- carpal scaphoid