VENTRALISATION Flashcards
NEURAL PLATE BORDER CELLS BECOME THAT DO NOT MIGRATE BECOME WHAT
ROOF PLATE CELLS
WHAT DO ROOF PLATE CELLS BEGIN TO UPREGULATE
BMPS
WHAT DO BMPS MADE IN THE ROOFPLATE DO
THEY ARE SECRETED AND DIFFUSE INTO THE DORSAL NEURAL TUBE
WHAT DOES SECRETION OF BMP INTO THE DORSAL NEURAL TUBE DO
INDUCES TRANSCRIPTION OF OTHER TRANSCRIPTION FACTORS SUCH AS PAX6 PAX7 PAX3 THAT CAUSE NERUAL TUBE PROGENITORS TO ACQUIRE DORSAL IDENTITIES
WHERE IS THE NODE IN RELATION TO THE NEURAL TUBE
SITS BELOW THE VENTRAL MIDLINE OF TEH NEURAL TUBE
WHAT SECRETED FACTOR FROM THE NOTOCHORD GIVES RISE TO THE FLOOR PLATE CELLS IN THE NEURAL TUBE.
SONIC HEDGEHOG
WHAT DOES SONIC HH SIGNALLING DO
SHH SIGNALLING INDUCES EXPRESSION OF TFS IN PROGENITOR CELLS THAT WILL CONFER VENTRAL NERUAL TUBE IDENTITY.
DIFFERENT CONCENTRATIONS OF MORPHOGENS/SECRETED MOLECULES ETC GIVE RISE TO WHAT
DISCRETE SEGMENTED LAYERS ALONG THE AXES
IF A PROGENITOR CELL UPREGULATES NKX6.1 AND OLIG2 WHAT WILL IT GIVE RISE TO
A DIFFERENTIATED MOTOR NEURON
WHAT IS THE OVERALL FUNCTION OF SONIC HH
TO CONFER A DV PATTERN OF TRANSCRIPTION FACTORS ON PROGENITOR CELLS. THESE TFS ARE THE UPSTREAM MASTER REGULATORS OF PARTICULAR NEURONAL FATES
SENSORY NEURONS COME FROM
NEURAL CREST CELLS
INTER NEURONS (DORSAL) COME FROM
THE INFLUENCE OF BMPS
MOTOR NEURONS COME FROM
INFLUENCE OF SHH
AFTER A NEURON HAS DIFFERENTIATED WHAT HAPPENS
WILL BEGIN TO PROJECT AXONS THAT FOLLOW PATHWAYS TO TARGET CELLS
