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MOAYAD - Dermatology Topics > Venereology > Flashcards

Venereology Flashcards

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1
Q

Clinical categorices for HIV ( CAT A )?

A
  • Acute retroviral infection.
  • Asymptomatic HIV infection.
  • Persistent generalized lymphadenopathy.
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2
Q

Papular rash in 2ndary syphilis may mimic ?

A
  • Psoriasis.
  • Lichen planus.

and i guess there is more.

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3
Q

N.gonorrhea predominantly involves ?

A

The columnar epithelium of urethra, endocervix, rectum, pharynx and conjuctivites.

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4
Q

Reiter’s syndrome?

A
  • HLA-B 27, more frequent in men.
  • Triads : urethritis, arthritis and conjunctivitis.
  • erosions on oral mucosa.
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5
Q

When to start ttt for HIV? according to european AIDS clinical society (EACS) ?

A
  • CAT B or C symptoms.
  • In asymptomatic patients if: ( CD4= 350-500) or (viral load > 100,000 copies)
  • Co-infection with HCV.
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6
Q

Symptoms of gonorrhea in women are ?

A
  • Cervicitis.**
  • Urethritis.
  • Proctitis.
  • Oropharyngitis.
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7
Q

Clinical categorices for HIV ( CAT C )?

A
  • INVASIVE CERVICAL CANCER.
  • SEVERE HSV INFECTION (>1month)
  • KAPOSI SARCOMA.
  • Lymphoma.
  • Candidiasis of esophagus, larynx and lungs.
  • Histoplasmosis.
  • Coccidioidomycosis.
  • Isosporisis.
  • Cryptococcosis.
  • CMV infection.
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8
Q

Patients with acute retroviral infection may have ?

A
  • Fever.
  • Lymphoadenopathy.
  • maculo-papular rash.
  • Neurological abnormalities.
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9
Q

HIV screening test and confirmatory test?

A
  • Screening: ELISA, 4th generation (p24).

- Confirmation: Western blot

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10
Q

Condylomata lata TTT?

A

Penicillin.

  • its Secondary syphilis.
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11
Q

condylomata accuminata TTT?

A
  • Condyline.
  • Imiquimod.
  • Cryotherapy.
  • Laser therapy.
  • Podophylin.
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12
Q

Epididymitis ?

A
  • Unilateral (on one side)
  • Pain, edema, erythema.
  • Difficulties in establishing borders of the testis (on palpation)
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13
Q

Complication of gonorrhea in men?

A
  • Tysonitis.
  • Cowperitis.
  • Gonorrhea disseminata.
  • Arthritis.
  • Abscessus periurethralis.
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14
Q

Anogenital warts caused by ?

A

HPV 6 and 11.

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15
Q

Trichomoniasis/Genital candidiasis predominantly invades ?

A

Stratified squamous epithelium.

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16
Q

condylomata acuminata caused by?

A
  • HPV 6,11.
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17
Q

Neurosyphilis ?

A
  • CNS involvement can occur during ANY STAGE OF SYPHILIS.

- No single test can be used to diagnose it (VDRL is highly specific but it is INsensitive )

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18
Q

Symptoms of gonorrhea in newborn are ?

A
  • Conjunctivitis.**
  • Oropharyngitis.
  • Proctitis.
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19
Q

Symptoms of gonorrhea in children are ?

A
  • Vaginitis.
  • Urethritis.
  • Proctitis.
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20
Q

Symptoms of gonorrhea in men are ?

A
  • Urethritis.
  • Proctitis.
  • Oropharyngitis.
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21
Q

Tertiary syphilis refers to ?

A
  • Gummata (cutaneous and mucosal lesions)

- CV syphilis.

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22
Q

Clinical categorices for HIV ( CAT B )?

  • Just read it! its too much
A
  • Unusual symptoms of common disorders (severe course, lack of response to the tt).
  • Suggestive of depressed cell-mediated immunity.
  • Hairy leuplakia.**
  • PID.
  • Bacterial angiomatosis.
  • Candidiasis.
  • CIN 2/3 and carcinoma in situ.
  • Zoster.
  • Idiopathic thrombocytopenic purpura.
  • Listeriosis.
  • Neuropathy.
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23
Q

In congenital syphilis treatment decisions frequently must be made on the basis of ?

A
  • Identification of syphilis in the mother.
  • Adequacy of maternal treatment.
  • Presence of clinical, laboratory, or radiographic evidence of syphilis in the infant
  • Comparison of maternal (after delivery) and infant nontreponemal serologic tests by using the same test and preferably the same laboratory.
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24
Q

What are the complication of the primary syphilis ?

A
  • Phimosis.
  • Paraphimosis.
  • Oedema induratum.
  • 2ndary infections.
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25
Q

Rieter’s syndrome?

A
  • its a complication of Chlamydia infection.
  • HLA-B 27, more frequent in men.
  • Triads: urethritis, arthritis and conjunctivitis.
26
Q

Fish-like smell discharge is characteristic for ?

A

Gardnellosis in women.

27
Q

Congenital syphilis division ?

A
  • Early (1st two yrs)

- Late (incl. stigmata of congenital syphilis)

28
Q

Nontreponemal tests for syphilis ?

A
  • VDRL. ( correlate the disease activity )

- RPR.

29
Q

Sugar fermentation tests results for (N.gonorrhea & N.Meningitidis) ?

A
  • N.gonorrhea: Glucose.

- N.Meningitidis: Glucose and maltose.

30
Q

Kaposi sarcoma - internal organ involvement ?

A
  • Lungs.
  • Liver.
  • Colon.
  • Spleen.
  • CNS.
31
Q

Difference between primary lesion in congenital syphilis and acquired syphilis ?

A
  • Vesicle
32
Q

Sings and symptoms of syphilis stages ?

A
  • Primary infection: Ulcer or chancre at the site of infection.
  • Secondary infections: skin rash, mucocutaneous lesions and lymphadenopathy.
  • Tertiary infection: Cardiac or ophthalmic manifestations, auditory abnormalities or gummatous lesions.
  • Latent infections: ( lacking clinical manifestations ) are detected by serologic tests.
33
Q

DOC of Chlamydial infection?

A
  • Doxycycline.
34
Q

Complication of gonorrhea in women?

A
  • Gonorrhea disseminata.

- Arthritis.

35
Q

How to screen for Congenital syphilis?

A
  • Capita IgM (IgM FTA-ABS).
  • Serologic testing of the mother’s serum is preferred rather than testing of the infant’s serum.
  • Screening of newborn serum or umbilical cord blood is NOT recommended.
36
Q

Neurosyphilis TTT ?

A

Aqueous crystalline penicillin G.

37
Q

Routine tests for syphilis should be taken in ?

A
  • All pregnant women.
  • ppl donating blood.
  • ppl with high risk for syphilis (STI, HIV, hep B & C)
  • pts suspected of early neurosyphilis.
  • risky sexual behaviour (MSM).
  • Should be offered to all attendees st dermato/venereology …
38
Q

Kaposi sarcoma types?

A
  • Classical.
  • Endemic.
  • Iatrogenic (immunosuppression)
  • Epidemic (AIDS) (HHV8)
39
Q

Vulvar intraepithelial neaplasia (VIN) caused by?

A
  • VIN 1: majority HPV 6 and 11.
  • VIN 2 or 3: HPV 16 and 18.
  • Incidence of VIN is increasing.
  • mean age of women with VIN is decreasing.
40
Q

Late Congenital syphilis ?

A
  • Osteoperiostitis.
  • Saber shins.
  • Hutchinson incisors.
  • clutton’s joints.
  • Keratitis parenchymatsa. (vascularisation of the cornea)
  • Internal organ involvement.
41
Q

Leucoderma syphiliticum ?

A
  • Between 4 months - 2 yrs.
  • Macular, oval depigmentations.
  • On the neck and shoulders.
  • Without symptoms.
  • Spontaneous regression after 4-6 months.
42
Q

Neurosyphilis CSF ?

A
  • elevated WBC (>5 mm3) (sensitive measure of the effectiveness of therapy)
  • Protein concentration >40 mg/dl.
43
Q

What tests are definitive methods for diagnosing early syphilis ?

A
  • Dark field examination (DFA) and direct fluorescent.
44
Q

Alopecia syphilitica ?

A
  • Usually after 6 months. (lasts 6-12 months)
  • sometimes the only symptom of syphilis.
  • Macular or diifuse.
  • Spontaneous regression.
45
Q

When does the sexual transmission of T.pallidum “syphilis” occurs?

A

ONLY when mucocutaneous syphilitic lesions are present. (uncommon after 1st two yrs of infection)

46
Q

uncomplicated N.gonorrhea ttt?

A
  • Ceftriaxone.

- Azithromycin.

47
Q

Non-Gonorrheal urethritis is most frequently caused by ?

A

Chlamydia trachomatis.

48
Q

most common STI ?

A

HPV

49
Q

Difference between primary lesion in adult secondary syphilis and congenital syphilis ?

A

Vesicular and bullous lesions.

50
Q

TTT of Trichomoniasis ?

A
  • Tinidazolum.

- Metronidazole

51
Q

Treponemal tests for syphilis ?

A
  • FTA-ABS.
  • TP-PA
  • Does NOT correlate with the disease activity and should NOT be used to assess TTT response.
  • serofast reaction
52
Q

Cervical cancer caused by?

A
  • HPV 16 (70%) and 18. etc…
53
Q

C. trachomatis,

  • Incubation period?
  • Presumptive diagnosis?
  • Confirmatory diagnosis ?
A
  • 2-7 wks.
  • Presumptive diagnosis: Methylen blue stain, Gram stain.
  • diagnosis: direct immunoflurescent.
54
Q

N. gonorrhea,

  • Incubation period?
  • Presumptive diagnosis?
  • Confirmatory diagnosis ?
A
  • 2-7 days.
  • Presumptive diagnosis: Methylen blue stain, Gram stain.
  • Confirmatory diagnosis: culture on selective media and Positive oxidase reaction.
55
Q

TTT of Gardnellosis?

A

Metronidazole

56
Q

Buschke-Löwenstein condylomata ?

A
  • HPV 6,11.

- An intermediate entity between “ordinary” condylomata acuminata and verrucous carcinoma.

57
Q

Duration of syphilis stages ?

A
  • Primary syphilis: up to 9 weeks.
  • Early secondary syphilis: 9-16 weeks.
  • Late secondary syphilis: 16 wks - 1 yr.
  • Early latent syphilis: up to 1 yr.
58
Q

Describe primary lesion in syphilis?

A
  • Within 3-4 weeks.
  • Usually single lesion.
  • PAINLESS.
  • 5-15 mm.
  • Very well marked borders.
  • Oval.
  • Hard on palpation.
  • Healing within 3-4 weeks.
  • Enlargement of regional lymph nodes.
59
Q

Complication of Chlamydial infection?

A

Reiter’s syndrome.

60
Q

Early Congenital syphilis ?

A
  • lesions is similar to those of secondary syphilis.

- in contrast to adult 2ndary syphilis, CS may have vesicular or bullous lesions (palms and soles).

MOAYAD - Dermatology Topics (22 decks)

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