Venereology Flashcards
1
Q
Clinical categorices for HIV ( CAT A )?
A
- Acute retroviral infection.
- Asymptomatic HIV infection.
- Persistent generalized lymphadenopathy.
2
Q
Papular rash in 2ndary syphilis may mimic ?
A
- Psoriasis.
- Lichen planus.
and i guess there is more.
3
Q
N.gonorrhea predominantly involves ?
A
The columnar epithelium of urethra, endocervix, rectum, pharynx and conjuctivites.
4
Q
Reiter’s syndrome?
A
- HLA-B 27, more frequent in men.
- Triads : urethritis, arthritis and conjunctivitis.
- erosions on oral mucosa.
5
Q
When to start ttt for HIV? according to european AIDS clinical society (EACS) ?
A
- CAT B or C symptoms.
- In asymptomatic patients if: ( CD4= 350-500) or (viral load > 100,000 copies)
- Co-infection with HCV.
6
Q
Symptoms of gonorrhea in women are ?
A
- Cervicitis.**
- Urethritis.
- Proctitis.
- Oropharyngitis.
7
Q
Clinical categorices for HIV ( CAT C )?
A
- INVASIVE CERVICAL CANCER.
- SEVERE HSV INFECTION (>1month)
- KAPOSI SARCOMA.
- Lymphoma.
- Candidiasis of esophagus, larynx and lungs.
- Histoplasmosis.
- Coccidioidomycosis.
- Isosporisis.
- Cryptococcosis.
- CMV infection.
8
Q
Patients with acute retroviral infection may have ?
A
- Fever.
- Lymphoadenopathy.
- maculo-papular rash.
- Neurological abnormalities.
9
Q
HIV screening test and confirmatory test?
A
- Screening: ELISA, 4th generation (p24).
- Confirmation: Western blot
10
Q
Condylomata lata TTT?
A
Penicillin.
- its Secondary syphilis.
11
Q
condylomata accuminata TTT?
A
- Condyline.
- Imiquimod.
- Cryotherapy.
- Laser therapy.
- Podophylin.
12
Q
Epididymitis ?
A
- Unilateral (on one side)
- Pain, edema, erythema.
- Difficulties in establishing borders of the testis (on palpation)
13
Q
Complication of gonorrhea in men?
A
- Tysonitis.
- Cowperitis.
- Gonorrhea disseminata.
- Arthritis.
- Abscessus periurethralis.
14
Q
Anogenital warts caused by ?
A
HPV 6 and 11.
15
Q
Trichomoniasis/Genital candidiasis predominantly invades ?
A
Stratified squamous epithelium.
16
Q
condylomata acuminata caused by?
A
- HPV 6,11.
17
Q
Neurosyphilis ?
A
- CNS involvement can occur during ANY STAGE OF SYPHILIS.
- No single test can be used to diagnose it (VDRL is highly specific but it is INsensitive )
18
Q
Symptoms of gonorrhea in newborn are ?
A
- Conjunctivitis.**
- Oropharyngitis.
- Proctitis.
19
Q
Symptoms of gonorrhea in children are ?
A
- Vaginitis.
- Urethritis.
- Proctitis.
20
Q
Symptoms of gonorrhea in men are ?
A
- Urethritis.
- Proctitis.
- Oropharyngitis.
21
Q
Tertiary syphilis refers to ?
A
- Gummata (cutaneous and mucosal lesions)
- CV syphilis.
22
Q
Clinical categorices for HIV ( CAT B )?
- Just read it! its too much
A
- Unusual symptoms of common disorders (severe course, lack of response to the tt).
- Suggestive of depressed cell-mediated immunity.
- Hairy leuplakia.**
- PID.
- Bacterial angiomatosis.
- Candidiasis.
- CIN 2/3 and carcinoma in situ.
- Zoster.
- Idiopathic thrombocytopenic purpura.
- Listeriosis.
- Neuropathy.
23
Q
In congenital syphilis treatment decisions frequently must be made on the basis of ?
A
- Identification of syphilis in the mother.
- Adequacy of maternal treatment.
- Presence of clinical, laboratory, or radiographic evidence of syphilis in the infant
- Comparison of maternal (after delivery) and infant nontreponemal serologic tests by using the same test and preferably the same laboratory.
24
Q
What are the complication of the primary syphilis ?
A
- Phimosis.
- Paraphimosis.
- Oedema induratum.
- 2ndary infections.
25
Rieter's syndrome?
- its a complication of Chlamydia infection.
- HLA-B 27, more frequent in men.
- Triads: urethritis, arthritis and conjunctivitis.
26
Fish-like smell discharge is characteristic for ?
Gardnellosis in women.
27
Congenital syphilis division ?
- Early (1st two yrs)
| - Late (incl. stigmata of congenital syphilis)
28
Nontreponemal tests for syphilis ?
- VDRL. ( correlate the disease activity )
| - RPR.
29
Sugar fermentation tests results for (N.gonorrhea & N.Meningitidis) ?
- N.gonorrhea: Glucose.
| - N.Meningitidis: Glucose and maltose.
30
Kaposi sarcoma - internal organ involvement ?
- Lungs.
- Liver.
- Colon.
- Spleen.
- CNS.
31
Difference between primary lesion in congenital syphilis and acquired syphilis ?
- Vesicle
32
Sings and symptoms of syphilis stages ?
- Primary infection: Ulcer or chancre at the site of infection.
- Secondary infections: skin rash, mucocutaneous lesions and lymphadenopathy.
- Tertiary infection: Cardiac or ophthalmic manifestations, auditory abnormalities or gummatous lesions.
- Latent infections: ( lacking clinical manifestations ) are detected by serologic tests.
33
DOC of Chlamydial infection?
- Doxycycline.
34
Complication of gonorrhea in women?
- Gonorrhea disseminata.
| - Arthritis.
35
How to screen for Congenital syphilis?
- Capita IgM (IgM FTA-ABS).
- Serologic testing of the mother's serum is preferred rather than testing of the infant's serum.
* Screening of newborn serum or umbilical cord blood is NOT recommended.
36
Neurosyphilis TTT ?
Aqueous crystalline penicillin G.
37
Routine tests for syphilis should be taken in ?
- All pregnant women.
- ppl donating blood.
- ppl with high risk for syphilis (STI, HIV, hep B & C)
- pts suspected of early neurosyphilis.
- risky sexual behaviour (MSM).
- Should be offered to all attendees st dermato/venereology ...
38
Kaposi sarcoma types?
- Classical.
- Endemic.
- Iatrogenic (immunosuppression)
- Epidemic (AIDS) (HHV8)
39
Vulvar intraepithelial neaplasia (VIN) caused by?
- VIN 1: majority HPV 6 and 11.
- VIN 2 or 3: HPV 16 and 18.
- Incidence of VIN is increasing.
- mean age of women with VIN is decreasing.
40
Late Congenital syphilis ?
- Osteoperiostitis.
- Saber shins.
- Hutchinson incisors.
- clutton's joints.
- Keratitis parenchymatsa. (vascularisation of the cornea)
- Internal organ involvement.
41
Leucoderma syphiliticum ?
- Between 4 months - 2 yrs.
- Macular, oval depigmentations.
- On the neck and shoulders.
- Without symptoms.
- Spontaneous regression after 4-6 months.
42
Neurosyphilis CSF ?
- elevated WBC (>5 mm3) (sensitive measure of the effectiveness of therapy)
- Protein concentration >40 mg/dl.
43
What tests are definitive methods for diagnosing early syphilis ?
- Dark field examination (DFA) and direct fluorescent.
44
Alopecia syphilitica ?
- Usually after 6 months. (lasts 6-12 months)
- sometimes the only symptom of syphilis.
- Macular or diifuse.
- Spontaneous regression.
45
When does the sexual transmission of T.pallidum "syphilis" occurs?
ONLY when mucocutaneous syphilitic lesions are present. (uncommon after 1st two yrs of infection)
46
uncomplicated N.gonorrhea ttt?
- Ceftriaxone.
| - Azithromycin.
47
Non-Gonorrheal urethritis is most frequently caused by ?
Chlamydia trachomatis.
48
most common STI ?
HPV
49
Difference between primary lesion in adult secondary syphilis and congenital syphilis ?
Vesicular and bullous lesions.
50
TTT of Trichomoniasis ?
- Tinidazolum.
| - Metronidazole
51
Treponemal tests for syphilis ?
- FTA-ABS.
- TP-PA
* Does NOT correlate with the disease activity and should NOT be used to assess TTT response.
* serofast reaction
52
Cervical cancer caused by?
- HPV 16 (70%) and 18. etc...
53
C. trachomatis,
- Incubation period?
- Presumptive diagnosis?
- Confirmatory diagnosis ?
- 2-7 wks.
- Presumptive diagnosis: Methylen blue stain, Gram stain.
- diagnosis: direct immunoflurescent.
54
N. gonorrhea,
- Incubation period?
- Presumptive diagnosis?
- Confirmatory diagnosis ?
- 2-7 days.
- Presumptive diagnosis: Methylen blue stain, Gram stain.
- Confirmatory diagnosis: culture on selective media and Positive oxidase reaction.
55
TTT of Gardnellosis?
Metronidazole
56
Buschke-Löwenstein condylomata ?
- HPV 6,11.
| - An intermediate entity between "ordinary" condylomata acuminata and verrucous carcinoma.
57
Duration of syphilis stages ?
- Primary syphilis: up to 9 weeks.
- Early secondary syphilis: 9-16 weeks.
- Late secondary syphilis: 16 wks - 1 yr.
- Early latent syphilis: up to 1 yr.
58
Describe primary lesion in syphilis?
- Within 3-4 weeks.
- Usually single lesion.
- PAINLESS.
- 5-15 mm.
- Very well marked borders.
- Oval.
- Hard on palpation.
- Healing within 3-4 weeks.
- Enlargement of regional lymph nodes.
59
Complication of Chlamydial infection?
Reiter's syndrome.
60
Early Congenital syphilis ?
- lesions is similar to those of secondary syphilis.
| - in contrast to adult 2ndary syphilis, CS may have vesicular or bullous lesions (palms and soles).
