Lymphoma Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Pruritus in Large plaque parapsoriasis – poikilodermic variant is a symptom of ?

A

malignant transformation !!!

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2
Q

Clinical stages of Mycosis fungoides?

A
- Phase 1: Patch stage
Persistent scaly patches.
- Phase 2: Plaque stage
Infiltrative elevated lesions.
- Phase 3: Tumor stage
nodules
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3
Q

Which Parapsoriasis is with high risk of malignant transformation?

A
  • Large-plaque parapsoriasis.
  • Poikiloderma atrophicans vasculare.
  • And MF can develop in 20% of cases.
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4
Q

T cell lymphomas of

the skin are ?

A
  • mycosis fungoides.
  • Sezary syndrome.
  • Pagetoid reticulosis.
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5
Q

Mycosis fungoides diagnosis ?

A
  • clinical skin changes +
  • histopathology (collections of lymphocytes
    (Pautrier microabscess) 25%)
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6
Q

Mycosis fungoides treatment?

A

_accordingly to the stage of the disease:

  • Topical: moderate to potent corticosteroids, bexaroten, carmustine
  • Phototherapy: PUVA, Re-Puva, NB-UVA
  • Oral retinoids (baxaroten, acitretin)
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7
Q

Mycosis fungoides is :

A

T cell lymphoma

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8
Q

Large-plaque parapsoriasis biopsy ?

A
  • consider repeated biopsies, every six months.

- Pruritus!!! and elevation as indicators of transforamtion.

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9
Q

What is the risk of malignant transformation in Actinic keratoses?

A

10%

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10
Q

Which Parapsoriasis form does not progress to lymphoma?

A

Small-plaque parapsoriasis

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11
Q

Which erythrodermic leukemic manifestation

of T-cell lymphoma whith worse prognosis than MF?

A
  • Sezary syndrome.

5-yr survival – 10-20%

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12
Q

Three symptoms – classic triad of Sezary syndrome?

A
  • Erythroderma.
  • Lymphadenopathy.
  • Atypical lymphocytes Circulating in the blood.
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