General topics Flashcards
recommended margins for excisional biopsy for small BCC or SCC ?
4-5 mm
Acantosis nigricans is ?
A paraneoplastic disease.
The primary skin chromphores are ?
- Water.
- Hemoglobin.
- Melanin.
Cryosurgery?
is the process of destroying a skin lesion by freezing it with liquid nitrogen.
Biopsy site for ulcerated/necrotic lesion?
Edge of ulcer or necrosis plus adjacent skin.
Raynaud’s phenomenon can be found in ?
- Systemic sclerosis.
- SLE.
- Dermatomyositis.
What should be controlled during methotrexate therapy ?
Liver enzymes, morphology, lipids.
Herald pach is typical for ?
Pityriasis rosea
recommended margins for excisional biopsy for melanoma?
5mm
Necrobiosis lipoidica is?
a disease is strongly associated with diabetes mellitus.
Compulsive plucking of the hair is known as?
Trichtillomamania.
What is the most important role in the protection against transepidermal water loss is played by ?
Cornified layer
recommended margins for excisional biopsy for benign lesion?
1-2 mm
The target chromphore in vascular lesions is ?
Oxyhemoglobin.
- absorption peaks at 418,542 and 577 nm.
recommended margins for excisional biopsy for atypical nevi?
3-4 mm
Kobner phenomenon in ?
- Psoriasis.
- LP.
- Common warts.
- Plane warts.
- Could also be seen in Erythema multiforme.
Pityriasis versicolor is caused by:
Malassezia furfur, the pathogenic form of pityrosporum oval.
The most common indication for Q-switched laser?
Removing tatoos.
Lammellar ichtyosis ?
- Defect of transglutaminase 1.
- oral retinoids, glycolic acid.
- May lead to blindness.
- Halequin ichtyosis: usually fatal, oral retinoids.
Nikolsky’s sign is positive in ? ( name all )
- SSSS.
- TEN ( or Lyell syndrome ).
- SJS.
- Pemphigus vulgaris.
- Generalized psoriasis pustulosa (Von zumbusch).
- Burns.
Scarring (cicatricial) alopecia can be present in :
- Frontal fibrosing alopecia.
- Lichen planopilaris.
- Cutaneous lupus erythematous.
What is the most common used technique for obtaining a skin specimen for histologic examination ?
Shave biopsy.
Biopsy site for small vessels vasculitis ?
Characteristic lesion of recent onset.
Biopsy site for blister ?
Edge of lesion, including perilesional skin.
