4. Allergic Diseases ( Eczema, AD and urticaria ) Flashcards
In atopic dermatitis, one of the postulated pathomechanism is defect in ? “ loss of function” mutation ?
Filaggrin.
When does the Angioedema resolves in acute urticaria ?
with 72 hrs.
The most common cause that provokes acute urticaria ?
Food and drugs.
How long does the wheals last in urticaria ?
Less than 24 hrs.
Most common types of Physical urticaria?
- Dermographism: (reaction when the skin scratched)
- Cholinergic urticaria: (on exercise,overheating, hot water or stress)
- Delayed pressure urticaria.
TTT for urticaria ?
- Anti-histamine 1. “1st choice”
- Cyclosporine.
Which type of allergy is involved in urticaria ?
type 1
- also AD is type 1.
Typical locations for seborrheic dermatitis ?
- Eyebrows.
- Naso-labial folds.
- Scalp.
- Sternal area.
Pink, itchy or “burning” swellings (wheals) is characterised for ?
Urticaria.
What is the TTT for AD?
- Elimination of allergen.
- Topical treatment ( Emollients, steriods and calcineurin inhibitors )
- Systemic (steriods ttt only for short time) Antihistamine, tacrolimus, cyclosporine and tacrolimus.
- PUVA.
What are the uticaria classes ?
- Ordinary urticaria.
- Physical urticaria.
- Angioedema urticaria (without wheals)
- Contact urticaria.
- Urticarial vasculitis.
- Autoimmune urticaria.
what is the major criteria for atopic dermatitis ?
Hanifin&_Rajka:
- pruritus
- typical location ( flexural distribution )
- characteristic morphology of skin lesions
- coexistence with atopic diseases patient or his family
Angioedema may be dependent with disturbances in complement system. Which kind ?
C1 inhibitor deficiency.
What is the major effector cells in urticaria ?
mast cells
Which type of allergy is involved in allergic contact dermatitis “ACD” ?
type IV.
