vecuronium norcuron

Question 1

drug classification

Answer 1

non depolarizing neuromuscular blocker

Question 2

mechanism of action

Answer 2

niconinic ACh R antagonist-competes with ACh at neuromuscular junction and prevents binding thus inhibiting skeletal muscle depolarization

Question 3

onset

Answer 3

less then 1 minute

Question 4

peak

Answer 4

3-5 minutes

Question 5

duration

Answer 5

30 -80 minutes

Question 6

half life

Answer 6

30-80 min

Question 7

indications, field use

Answer 7

need for temporary paralysis to facilitate endotracheal intubation
need for continued paralysis following endotracheal intubation

Question 8

contraindications

Answer 8

hypersensitivity

Question 9

side effects, adverse reactions

Answer 9

bradycardia, hypotension

Question 10

dose adult

Answer 10

0.08-0.10mg/kg IV IO

Question 11

dose pedi

Answer 11

0.1 mg/kg IV IO

Question 12

precautions

Answer 12

presence of neuromuscular disease may be associated with prolonged paralysis

Question 13

drug on drug interactions

Answer 13

potentiated by lidocaine, procainamide, beta blockers, magnesium sulfate and other neuromuscular blockers