fentanyl citrat-sublimaze

Question 1

drug classification

Answer 1

narcotic analgesic

Question 2

mechanism of action

Answer 2

opiate R agonist-hyperpolarization of interneurons and decreased release of neurotransmitters responsible for the transmission of pain impulses to the thalamus and cerebral cortex

Question 3

onset

Answer 3

immediate

Question 4

peak

Answer 4

3-5 min IV IO

Question 5

duration

Answer 5

30-60 min

Question 6

half life

Answer 6

6-8 hours

Question 7

indications, field use

Answer 7

severe pain

adjunct for RSI

Question 8

contraindications

Answer 8

respiratory depression or insufficiency
uncorrected hypotension
known hypersensitivity

Question 9

side effects, adverse reactions

Answer 9

bradycardia, respiratory depression, apnea, chest wall rigidity

Question 10

dose adult

Answer 10

1 micro gram/kg slow IV IO IN, max single dose 100 micrograms-repeat after 10 min

Question 11

adult older than 65

Answer 11

0.5 micrograms/kg slow IV IO IN max single dose of 50 micrograms, repeat in 5 min

Question 12

pedi

Answer 12

1-2 micrograms/kg slow IV IO IN

Question 13

precautions

Answer 13

caution with patients with kidney and liver dysfunction

Question 14

drug on drug interactions

Answer 14

additive effects with CNS depressants

should not be given with patients using MAOI’s in the last 14 days- may cause serotonin syndrome