succinylcholine anectine

Question 1

drug classification

Answer 1

depolarizing neuromuscular blocker

Question 2

mechanism of action

Answer 2

nicotinic ACh R agonist- competes with ACh at neuromuscular junction. when bound, causes initial wave of widespread neuromuscular depolarization and prevents ACh binding and secondary muscle stimulation.

Question 3

onset

Answer 3

45-60 sec IV, 2-3 min IM

Question 4

peak

Answer 4

1-3 min

Question 5

duration

Answer 5

6-10 min IV, 10-30 min IM

Question 6

half life

Answer 6

5-10 min

Question 7

indications, field use

Answer 7

need for temporary paralysis to facilitate endotracheal intubation

Question 8

contraindications

Answer 8

penetrating eye injury,
narrow angle glaucoma
known or suspected hyperkalemia
history of malignant hyperthermia
history of myasthenia gravis

Question 9

side effects, adverse reactions

Answer 9

dysrhythmias, bradycardia, hypotension, increased intraocular pressure, increased icp

Question 10

dose adult

Answer 10

1-2mg/kg IV IO

Question 11

dose pedi

Answer 11

1mg/kg IV IO

Question 12

precautions

Answer 12

may cause dysrhythmias and cardiac arrest, particular in patients with hyperkalemia

Question 13

drug on drug interactions

Answer 13

potentiated by lidocaine, procainamide, beta blockers, magnesium sulfate, and other neuromuscular blockers