Vasculitis Flashcards
1
Q
What are the microscopic features of GCA?
A
Intimal thickening with luminal stenosis
Mononuclear cell infitrate into media with necrosis
Giant cell formation in the media
2
Q
What are the microscopic feature of polyartheritis nodosa?
A
Fibrinoid necrosis with thickening and infiltration of vessel wall
Neutrophils, eosinophils and lymphocytes may be present
Thrombi and aneursymal change may lead to necrosis
3
Q
How does ANCA positive vasculitis appear microscopically?
A
Focal necrosis, crescentic formation and paucity or absence of immunoglobulin deposites
