Vasculitides

Question 1

focal granulomatous inflammation of large vessels

Answer 1

giant cell (temporal) arteritis

Question 2

related to polymyalgia rheumatica

Answer 2

giant cell (temporal) arteritis

Question 3

granulomatous thickening and narrowing of aortic arch and proximal great vessels

Answer 3

Takayasu arteritis

Question 4

transmural inflammation of arterial wall with fibrinoid necrosis in different stages of inflammation + renal microaneurysms, primarily found in medium-sized renal/visceral vessels

Answer 4

polyarteritis nodosa

Question 5

coronary artery aneurysms

Answer 5

Kawasaki disease (mucocutaneous lymph node syndrome)

Question 6

segmental thrombosing vasculitis of medium-sized vessels

Answer 6

Buerger disease (thromboangiitis obliterans)

Question 7

focal necrotizing vasculitis, necrotizing granulomas in lung/upper airway, necrotizing glomerulonephritis, c(PR3)-ANCA

Answer 7

granulomatosis with polyangiitis (Wegener granulomatosis)

Question 8

necrotizing vasculitis of lung, kidney, and skin without nasopharyngeal involvement or granulomas, p(MPO)-ANCA

Answer 8

microscopic polyangiitis

Question 9

granulomatous, necrotizing vasculitis of small vessels with eosinophilia, p(MPO)-ANCA

Answer 9

eosinophilic granulomatsos with polyangiitis (Churg-Strauss)

Question 10

IgA complex deposition, associated with IgA nephropathy, usually follows UTI in kids

Answer 10

HSP

Question 11

telangiectasias, recurrent epistaxis, AVMs, GI bleeds/hematuria, skin discolorations

Answer 11

Osler-Weber-Rendu (hereditary hemorrhagic telangiectasia)