Toxicity Flashcards
antidote for acetaminophen
N-acetylcysteine (replenishes glutathione)
antidote for organophosphates (irreversible ACh inhibition)
atropine (muscarinic antagonist) and pralidoxime (PAM)
antidote for amphetamines
acidify urine with NH4Cl
antidote for antimuscarinics/anticholinergics
physostigmine and control hyperthermia
antidote for benzodiazepines
flumazenil
antidote for beta blockers
glucagon
antidote for CO
100% hyperbaric O2
antidote for Cu, As, Au
penicillamine
antidote for cyanide
nitrite + thiosulfate, hydroxocobalamin
antidote for digitalis
anti-dig Fab fragments
antidote for heparin
protamine sulfate
antidote for Fe
deferoxamine
antidote for Pb
EDTA, dimercaprol, succimer, penicillamine
antidote for Hg, As, Au
dimercaprol, succimer
antidote for methanol, ethylene glycol
fomepizole > ethanol, dialysis
antidote for methemoglobin
methylene blue, vitamin C
antidote for opioids
naloxone, naltrexone
antidote for salicylates
alkalinize urine with NaHCO3, dialysis
antidote for TCAs
plasma alkalinization with NaHCO3
antidote for tPA, streptokinase, urokinase
aminocaproic acid
antidote for warfarin
fresh frozen plasma followed by vitamin K
CYP450 inducers
- chronic alcohol
- St. John’s wort
- phenytoin
- phenobarbital
- nevirapine
- rifampin
- griseofulvin
- carbamazepine
Chronic alcoholics Steal Phen-Phen and Never Refuse Greasy Carbs.
CYP450 inhibitors
- acute alcohol
- ritonavir
- amiodarone
- cimetidine
- ketoconazole
- sulfonamides
- INH
- grapefruit juice
- quinidine
- macrolides
AA RACKS IN GQ Magazine.
sulfa drugs (for allergy purposes)
- acetazolamide, furosemide, thiazides
- celecoxib
- sulfonamide abx, sulfonylureas, sulfasalazine
