Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Psych Drugs > Flashcards

Psych Drugs Flashcards

1
Q

fluoxetine

A

SSRI - used for depression in pregnant women and children/adolescents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

sertraline

A

SSRI - used for depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

paroxetine

A

SSRI - used for depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

fluvoxamine

A

SSRI - used for OCD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

citalopram

A

SSRI - used for depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

escitalopram

A

SSRI - used for depression and GAD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

venlafaxine

A

SNRI - used for depression, GAD, neuropathic pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

duloxetine

A

SNRI - used for depression, neuropathic pain, fibromyalgia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

buproprion

A

NE/DA reuptake inh - used for depression and smoking cessation, will not cause sexual side effects so good for younger patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

trazodone

A

used in MDD, insomnia - no sexual side effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

mirtazapine

A

a2 antagonist - useful in MDD especially those with weight loss and insomnia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

amitriptyline

A

tertiary amine (TCA) - chronic pain, migraines, insomnia

TCAs prevent reuptake of NE and serotonin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

imipramine

A

tertiary amine (TCA) - enuresis, panic disorder

TCAs prevent reuptake of NE and serotonin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

clomipramine

A

tertiary amine (TCA) - OCD

TCAs prevent reuptake of NE and serotonin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

doxepin

A

tertiary amine (TCA) - chronic pain, insomnia

TCAs prevent reuptake of NE and serotonin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

nortriptyline

A

secondary amine (TCA) - chronic pain

TCAs prevent reuptake of NE and serotonin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

desipramine

A

secondary amine (TCA)

TCAs prevent reuptake of NE and serotonin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

common SSRI SEs

A
  • GI upset
  • insomnia
  • HA
  • anorexia –> weight loss
  • sexual dysfunction
  • akathisia-like restlessness
  • serotonin syndrome - fever, diaphoresis, tachycardia, hypertension, delirium, hyperreflexia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

common SNRI SEs

A
  • same as SSRI

- due to NE, hypertension, dry mouth, constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

trazodone SEs

A

orthostatic hypotension, arrhythmias, priapism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

mirtazapine SEs

A

sedation, weight gain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

common TCA SEs

A
  • anticholinergic - dry mouth, constipation, urinary retention, blurred vision, tachycardia
  • antihistaminergic - sedation, weight gain
  • antiadrenergic - orthostatic hypotension, reflex tachycardia, arrhythmias
  • serotonergic - sexual SEs like SSRIs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

phenelzine

A

MAO-I - refractory depression and anxiety

prevent inactivation of catecholamines (NE, DA, 5-HT, tyramine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

tranylcypromine

A

MAO-I - refractory depression and anxiety

prevent inactivation of catecholamines (NE, DA, 5-HT, tyramine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

isocarboxazid

A

MAO-I - refractory depression and anxiety

prevent inactivation of catecholamines (NE, DA, 5-HT, tyramine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

common MAO-I SEs

A
  • 5-HT syndrome when taken with SSRI (wait at least 2 wks before switching from SSRI –> MAO-I)
  • hypertensive crisis when tyramine rich foods or sympathomimetics are on board
  • orthostatic hypotension
  • sedation, sleep dysfunction
  • weight gain
  • sexual dysfunction
  • supplement B6 to prevent peripheral neuropathy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

mechanism of typical antipsychotics

A

D2 antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

mechanism of atypical antipsychotics

A

D2 and 5-HT-2A antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

chlorpromazine

A
  • low potency typical antipsychotic
  • higher incidence of antiadrenergic, anticholinergic, and antihistaminic side effects
  • lower incidence of EPS and NMS
  • blue-grey skin discoloration
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

haloperidol

A
  • high potency typical antipsychotic
  • lower incidence of antiadrenergic, anticholinergic, and antihistaminic side effects
  • higher incidence of EPS and NMS
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

common SEs of typical antipsychotics

A
  • mesocortical - makes negative symptoms worse, de-motivation
  • nigrostriatal - EPS (akathisia, dystonia, parkinsonism)
  • tubuloinfundibular - hyperprolactinemia
  • antihistaminic - sedation, weight gain
  • antiadrenergic - orthostatic hypotension, cardiac arrythmias
  • anticholinergic - dry mouth, tachycardia, urinary retention, blurry vision, constipation
  • TD - often permanent choreoathetoid mvmts of tongue and mouth as a result of > 6 mos of use
  • NMS - fever, autonomic instability, leukocytosis, tremor, elevated CK, rigidity, delirium, diaphoresis
  • hepatotoxicity
  • seizure threshold is lower
  • QTc prolongation
32
Q

buproprion SEs

A
  • increased anxiety (avoid in eating disorders)

- lower seizure threshold (avoid in epilepsy)

33
Q

common SEs atypical antipsychotics

A
  • metabolic syndrome - follow weight, waist circumference, FLP, BG
  • QTc prolongation
  • hepatotoxicity
34
Q

atypical antipsychotics include (in decreasing order of metabolic risk):

A
  • clozapine - treatment refractory schizophrenia, very low risk of agranulocytosis, only antipsychotic that helps to decrase risk of suicide
  • olanzapine
  • quetiapine
  • paliperidone
  • ziprasidone
  • aripiprazole
35
Q

Li+

A

mood stabilizer used to treat acute mania, prevent relapse of manic episodes/depressive episodes in bipolar d/o, and decrease suicidality

36
Q

Prior to prescribing Li+, pt should have what tests? Because of what SEs?

A
  • EKG - arrythmias
  • BMP - nephrogenic DI and renal toxicity
  • TFT - hypothyroidism
  • CBC - leukocytosis
  • pregnancy test - Ebstein’s anomaly in fetus
37
Q

Check blood level of Li+ after ____ days.

A

5

38
Q

carbamazepine

A

anticonvulsant used to treat mania with mixed features and rapid cycling bipolar d/o

39
Q

mechanism of carbamazepine

A

Na+ channel antagonist

40
Q

What labs to order and common SEs of carbamazepine?

A
  • CBC, LFTs, pregnancy test
  • GI upset, CNS sedation, SJS
  • leukopenia, aplastic anemia, thrombocytopenia, agranulocytosis
  • hyponatremia
  • hepatitis
  • neural tube defects in fetus
41
Q

Carbamazepine ____ it’s own metabolism.

A

auto-induces

42
Q

valproic acid

A

mood stabilizer used to treat acute mania, mania with mixed features, and rapid cycling bipolar d/o

43
Q

mechanism of valproic acid

A

Na+ channel antagonist, potentiates GABA activity

44
Q

Check valproic acid levels after ____ days.

A

4-5

45
Q

Labs to order and common SEs of valproic acid

A
  • LFTs - hepatotoxicity
  • CBC - thrombocytopenia
  • pregnancy test - neural tube defects
46
Q

lamotrigine

A

mood stabilizer used ONLY for depressive episodes of bipolar d/o

47
Q

mechanism of lamotrigine

A

works on Na+ channels that modulate glutamate and aspartate

48
Q

concerning SE of lamotrigine

A

SJS

49
Q

oxcarbazepine

A

mood stabilizer that functions like carbamazepine and is better tolerated (only has risk of hyponatremia)

50
Q

gabapentin, pregabalin

A

helps with GAD, sleep, neuropathic pain, fibromyalgia

51
Q

topiramate

A

mood stabilizer that helps with impulse control disorders

52
Q

common SEs of topiramate

A
  • weight loss
  • met acid
  • kidney stones
  • cognitive slowing
53
Q

Which benzos are not metabolized by the liver?

A

lorazepam, oxazepam, temazepam

54
Q

diazepam

A

long acting benzo used for alcohol withdrawal, benzo/barb withdrawal, seizures

55
Q

clonazepam

A

long acting benzo used for anxiety, panic attacks

56
Q

alprazolam

A

int acting benzo used for anxiety, panic attacks

57
Q

lorazepam

A

int benzo used to treat panic attacks, alcohol/benzo/barb withdrawal

58
Q

oxazepam

A

int benzo used to treat alcohol/benzo/barb withdrawal

59
Q

temazepam

A

int benzo used to treat alcohol/benzo/barb withdrawal

60
Q

triazolam

A

short acting benzo used for insomnia

61
Q

midazolam

A

short acting benzo

62
Q

zolpidem/zaleplon/eszopiclone

A
  • bind to omega-1 receptor on GABA-A receptor to cause sedation
  • used for short-term treatment of insomnia
63
Q

diphenhydramine

A

antihistamine with anticholinergic effects

64
Q

ramelteon

A

melatonin agonist used for insomnia

65
Q

buspirone

A
  • partial 5-HT-1A agonist used for augmentation of GAD

- especially useful in alcoholics who cannot take benzos

66
Q

hydroxyzine

A

short acting antihistamine and anticholinergic effects used for anxiety

67
Q

In psychiatry, B blockers are used for:

A
  • panic attacks
  • performance anxiety
  • akathisia
68
Q

D-amphetamine

A

stimulant used for ADHD - watch BP, weight loss, insomnia, tic exacerbation, decreased seizure threshold

69
Q

methylphenidate

A

stimulant used for ADHD - watch BP, weight loss, insomnia, tic exacerbation, decreased seizure threshold

70
Q

atomoxetine

A

stimulant (inhibits NE, DA reuptake) used in ADHD

71
Q

modafinil

A

stimulant used in narcolepsy

72
Q

donepezil

A

AChesterase inh used in dementia

73
Q

galantamine

A

AChesterase inh used in dementia

74
Q

rivastigmine

A

AChesterase inh used in dementia

75
Q

memantine

A

NMDA glutamate antagonist used in dementia to be used WITH AChesterase inh

76
Q

ECT should be used for:

A
  • refractory depression (esp with psychotic features)
  • catatonia
  • acute mania
77
Q

light therapy is used to treat:

A

MDD with seasonal pattern

Pharmacology (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions