Valvular Heart Disease (VHD): AR/AS Flashcards

1
Q

the most common etiology of AS in the US is _____

A

calcific AS of a normal trileaflet valve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

AS is the most common primary valve disease and is best evaluated with echo. T or F ?

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

aortic _____ is a thickened AoV that still opens well, with a peak velocity < or = 2.5 m/s

A

sclerosis
*note:
- sclerosis: thickened AoV without decreased excursion. it may or may not become stenotic in the future.

  • stenosis: thickened AoV with decreased excursion
  • peak velocity > or = 2.6 m/s
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

bicuspid AS usually becomes symptomatic between the ages of ______

A

20-50 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

____ AS originates at the aortic valve cusps and moves out toward the commissures

A

Rheumatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what type of murmur is associated with AS ?

A

systolic crescendo decrescendo murmur

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

serial echocardiograms track changes in the AS patient, to include____

  1. AS peak velocity
  2. CO
  3. pressure half time
  4. RVSP
A

1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

the echo report on AS should include details regarding the _______ (3 parameters)

A
  1. level of obstruction
  2. LV size, wall thickness, and EF
  3. cusps mobility, thickness, calcification
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

_____ is a minimally invasive procedure that uses a balloon catheter with a stent-mounted valve crimped on its tip.

A

TAVR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is TAVR ?

A

Transcatheter aortic valve replacement (TAVR) is a procedure that replaces a diseased aortic valve with a man-made valve. Aortic valve replacement can also be performed with open-heart surgery; this procedure is surgical aortic valve replacement (SAVR).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

the patient is 84 years old and echo findings include thickened, calcified AoV cusps, LVH, LV enlargement, decreased LV systolic function, and post stenotic dilatation of the AoR; what is most likely the diagnosis?

A

degenerative AS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

when is raphe present?

A

BAV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what would you expect to see on the M-mode of a BAV ?

A

eccentric closure *either higher or lower

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

in the echo lab, we use Bernoulli’s equation to describe the relationship between pressure and velocity. the simplified Bernoulli’s equation = ________

A

4 (V)2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

the AV Doppler waveform is below the baseline from every window. T or F ?

A

F
above the baseline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

in order to acquire a quick maximum PG, the sonographer can utilize the modified Bernoulli’s equation (4V). T or F ?

A

F
use VTI with CW

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

according to the continuity equation, AVA = _______

A

AVA = (VTI LVOT) (CSA LVOT) / (VTI AoV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what are the 3 parameters required to assess AS ?

A
  1. LVOT diameter - used to calculate CSA = Pi (D LVOT/2)2
  2. AoV CW VTI - acquire AoV peak velocity
  3. LVOT PW VTI - acquire LVOT peak velocity

*note: continuity equation

V1 A1 = V2 A2
(VTI LVOT) (CSA LVOT) = (VTI AoV) (AVA)
solving for AVA..

AVA = (VTI LVOT) (CSA LVOT) / (VTI AoV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

the AVA by the continuity equation requires _____

A

VTI AoV with CW or PEDOF (required to get the highest velocity possible)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is the simplified continuity equation for AVA ?

A

AVA = [(.785)(D LVOT)2] (V LVOT) / (V AoV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

For AS assessment measurement, acquire ___ beats for normal sinus rhythm and ___ consecutive beats for irregular rhythm.

A

3+
5+

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what is the normal range of LVOT ?

A

1.8 - 2.2 cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

AS assessment:

acquire peak AoV velocity (VTI) with CW/PEDOF at multiple location: ___, ___, ___, & _____.

A

5C
3C
suprasternal
right parasternal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

AS can be over or underestimated by _____.

  1. 3-4+ AR
  2. improperly measured LVOT diameter
  3. tachycardia
  4. all of the above
A

4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

_____ seriously impact the AS severity scale and underestimates the AS peak velocity, consider using the AS velocity ratio.

A

reduced EF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

_____ would most likely cause chronic AR.

A

AS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

regular AR murmur vs severe AR murmur ?

A

regular: a high-pitched, blowing diastolic decrescendo murmur at the left sternal border
severe: a low-pitched, mid-diastolic, rumble at the apex

28
Q

another name for sever AR murmur ?

A

Austin Flint murmur

29
Q

echo findings include diastolic flutter of the AMVL and AoV cusps, early closure of the MV, and early opening of the AoV; what is most likely the diagnosis?

A

AR

30
Q

mild AR creates a flatter Doppler waveform with a higher pressure half-time. T or F ?

A

T

31
Q

severe, acute AR creates a sudden increase in preload and the heart is unable to compensate. increased preload causes the LVEDP (LV end-diastolic pressure) to exceed the LAP so the ____ closes early and ____ opens_____.

A

MV
AoV

32
Q

On M-mode, when AR travels through the closed cusps it creates _______.

A

abnormal diastolic flutter of AoV

33
Q

severe AR causes the aorta’s pressure to drop quickly, this creates a more rapid LV pressure increase and higher pressure half time. T or F ?

A

F

*severe AR - lower pressure half time

34
Q

the AR pressure half time is 300 m/s; what is most likely the diagnosis ?

A

moderate AR

35
Q

the AR peak velocity us usually 3+ m/s due to the pressure difference between the LV and aorta. T or F ?

A

T

36
Q

AS severity scale: peak velocity

mild value ?
severe value ?

A

mild: 2.6 - 2.9 m/s *note: 2.5 m/s = sclerosis

severe : > 4.0 m/s

37
Q

AS severity scale: mean PG

mild value ?
severe value ?

A

mild: < 20 mmHg

severe > 40 mHg

38
Q

AS severity scale: AVA

mild value ?
severe value ?

A

mild: > 1.5 cm2
severe: < 1.0 cm2

39
Q

AS severity scale: max PG

mild value ?

severe value ?

A

mild: 27-34 mmHg
severe: > 64 mmHg

40
Q

reduced EF underestimates the AoV peak velocity ad seriously impact the AS severity scale; with reduced EF, consider using the AS velocity ratio = __________ *unitless ratio

A

AS velocity ration = V LVOT / V AoV

*note:

mild AS: > 0.5

severe AS: < 0.25

41
Q

AR severity scale: pressure half time

mild value ?

severe value ?

A

mild: > 500 mmHg
severe: < 200 mmHg

42
Q

AR Doppler waveform vs MS waveform:

AR waveform is similar to the MS; however, contrary to the MS waveform where ______ (shape) is more severe, the ______ (shape) the AR waveform the more severe AR.

A

flatter
steeper

43
Q

What are are the abnormalities usually associated with quadricuspid valve?

A

PDA (patent ductus arteriosus)
Hypertrophic cardiomyopathy
Subaortic stenosis (thickening right before LVOT)
Ehler-Danlos syndrome
Coronary ostium displacement
Ventricular septal decect

*Note: coronary ostium (opeing to vessels)

The ostia of the left and right coronary arteries are located just above the aortic valve, as are the left and right sinuses of Valsalva.

Function:
Oxygenated blood is pumped into the aorta from the left ventricle; it then flows into the coronary artery ostia. Blood flow into the coronary arteries is greatest during ventricular diastole.

44
Q

What is Ehler-Danlos symdrome?

A

A group of inherited disorders that affect your connective tissues with 16 subtypes - primarily your skin, joints and blood vessel walls. Cardiac valvular type affects AoV & MV

45
Q

what are the etiologies of AR?

*primary leaflet abnormality

A
  1. congenital: BAV, quadricuspid/unicuspid valve, Rheumatic valvular disease
  2. degenerative: thickening/calcification due to age, myxomatous degeneration, leaflet damage due to membraneous subaortic stenosis
  3. infectious: bacterial endocarditis
  4. inflammatory: Rheumatic valvular disease, nonbacterial thrombotic endocarditis
  5. neoplastic: papillary fibroelastoma (benign cardiac tumor)
  6. traumatic: iatrogenic (relating illness caused by medical examination or treatment) cardiac catherization
  7. toxic: anorexigen (a drug that suppress the appetite) exposure
46
Q

what are the etiologies of AR?

*aortic root abnormalitiy

A
  1. genetic: Marfan syndrome, Loeys-Dietz syndrome, Ehlers-Danlos syndrome, Turner syndrome, familial thoracic aortic aneurysm syndrome)
  2. degenerative: aging, hypertension, atherosclerosis
  3. infectious: Syphilis, Salmonella, Staphylococci Mycobacteria
  4. inflammatory: Giant celll arthritis, Takayasu arthritis, RA, Spondyloathropathies
  5. traumatic: aortic dissection, VSD with cusp proplase
47
Q

acute vs chronic AR

what are the causes?

A

acute: dissection, infective endocarditis, trauma
chronic: aortic dilatation (Marfan syndrome, hypertension, Syphilis etc), AS, BAV, RHD, infective endocarditis, prosthetic valve dysfunction, other congenital anamolies

48
Q

acute vs chronic AR

what are the clinical presentation?

A

acute: pulmonary edema, refractory heart failure
chronic: often asymptomatic

49
Q

acute vs chronic AR

LV end-diastolic pressure

A

acute: markedly elevated; exceed LA pressure causing early MV closure & earlier AoV opening
chronic: normal to slightly elevated

50
Q

acute vs chronic AR

heart rate

A

acute: elevated
chronic: normal to slightly elevated - long-standing AR causes decreased LV function

51
Q

acute vs chronic AR

cardiac output

A

acute: decreased
chronic: normal

52
Q

acute vs chronic AR

diastolic pressure

A

acute: normal to slightly elevated
chronic: decreased

53
Q

acute vs chronic AR

systolic pressure

A

acute: normal to slightly decreased
chronic: elevated

54
Q

acute vs chronic AR

pressure and size difference

A

acute: size - normal, pressure - decreased in LV & increased in LA
chronic: size - increased, pressure - increased in LV & LA

55
Q

simplified Bernoulli Equation

A

ΔPmax (maximum pressure gradient) = 4 (Vmax)2

56
Q

modified Bernoulli Equation

A

ΔPmax = 4 (Vmax2 –VLVOT2)

57
Q

What does PISA stand for?

A

Proximal Isovelocity Surface Area

58
Q

Explain the steps for PISA

A
  1. Align direction of flow with insinuation beam 2. Zoom view & variance off 3. Change baseline/Nyquist limit low in direction of jet 4. Measure radius *Make sure AoV is closed!
59
Q

Explain the steps to measure vena contracta

A
  1. PLAX zoom view 2. Align jet to optimize VC imaging 3. Measure the narrowest jet diameter at or just apical to valve *Good at identifying mild or severe AR
60
Q

*Assessment of AR Explain the steps to quantify AR by CW

A
  1. Optimize Doppler angle with CW 2. Increase sweep speed 100m/s 3. Acquire AR peak velocity (average 3-5) 4. Acquire AR deceleration slope (average 3-5) *machine will calculate the AR pressure half time
61
Q

What is EROA ?

A

Effective Regurgitant Orifice Area *cross sectional area of VC = the narrowest area of actual flow

62
Q

EROA equation

A

EROA = regurgitant flow / peak velocity

63
Q

Regurgitant flow equation

A

Regurgitant flow = 2πr2 x VA (←color scale)

64
Q

*AR severity Color Doppler Mild & sever value?

A

Mild: < 25% Severe: > 65%

65
Q

*AR severity VC Mild & severe value ?

A

Mild: < 0.3 cm Severe: > 0.6 cm

66
Q

*AR severity EROA value Mild & severe?

A

Mild: < 0.1 cm2 Severe: > 0.3 cm2

67
Q

*AR severity PHT Mild & severe value ?

A

Mild: > 500m/s Severe: < 200m/s