Valve Disease Flashcards
Bicuspid incidence
1-2% general population
Majority never develop stenosis
Associated with coarctation
Bicuspid aortic stenosis
Look for AI and aortic dissection
Aortic stenosis
May be atherosclerotic
Severe stenosis late peaking with obscure s2
Pulses parvus tardus
Valve area
Cardiac out put/ heart rate x SEP x 44.3x square root of the gradient
Hakki
Cardiac out put/ square root of the gradient
Aortic stenosis
Mild velocity 1.5
Severe velocity >4m/sec gradient >40 valve area <1.0
Severe a symptomatic AS
Stress test is reasonable
AS follow up Change in symptoms Asymptomatic Yearly for severe AS Every 2 years got moderate AS Every 5 for mild
Expect
Jet velocity increase 0.3 m/sec
Gradient increSe 7 mmhg/ year
Valve area decrease 0.1 cm per year
AS symptoms and survival
Angina 5 years
Syncope 3 years
Failure 2 years
Low flow low gradient
10% cases
Dibutamine echo
Low flow Gorlin formula is wrong
Pseudo stenosis due to after load mismatch
Treatment of AS
Statin no benifit by saltire trial
Acei poss effect on inflammation
AVR
2-4% mortality in low risk
15-20% in high risk
TAVR indications
Severe AS
STS greater than 8%
Inoperable high risk
Life expectancy greater than 1 year
Bicuspid and aortic root
Replace aorta greater than 5.5 cm
Greater than 5 for rapid progression
Aorta greater than 4.5 with severe AS
AI severity
Vena contracts 0.6
Pressure half time mild >450 severe central jet width 65%,flow reversal > 0.6m/sec, Regurgitant volume >60ml, Regurgitant fraction > 55% EROA 0.3
Pressure half time 200 vena contracts >0.6 cm2
Acute AI
Tachycardia
Pulm edema
Short murmur
Diastolic MR
No IABP use nipride
AI presentation
Dyspnea
Angina due to decreased reserve
AI low EF
Need AVR
AI symptoms
Symptoms 25% a year
After symptoms death 10% a year
Chronic AI
Nifedipine and acei class 1
AI operative mortality
EF >50% 3.7%
35%. 6.7%
<35% 14%
AI indication for surgery
Symptoms
LV dysfunction 50
EDD>70(2b)
LVESD>55
MS
Evaluate for afib