Htn Flashcards

0
Q

PTA of the renals

A

5-10% people
Indicated for >75% bilateral disease
Improves BP in 60-70% usually fibromuscular.. Do not stent fibromuscular cases

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1
Q

BP increase in 20 mm systolic and 10 mm diastolic

A

Will double mortality

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2
Q

Coarctation

A
6-8% of the cases2-5x more in men
Increase in turners
Notching of the ribs 3 sign
Stent with 20 mm gradient 
Restenosis ?
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3
Q

Pheo

A
Best test 24 hour urine catecholamines and metanephrines positive test 2 fold normal 
10% malignant
10% extra abdominal 
10% multiple
MRI T2
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4
Q

Pheo treatment

A

Block alpha first phenoxy benzamine

Then beta blockers

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5
Q

Primary Aldo

A
Low plasma renin
PAC/PRA 30-40 for the diagnosis 
PAC>10 ng/dl
Treatment 
Spironolactone and eplerenone
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6
Q

Adrenergic system

A

Alpha1- vein constriction
Aloha2 venodation
Beta 1 increase ionotropy
Beta2 vaso dilation

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7
Q

Salt restriction

A

2-4 gm a day

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8
Q

Dash diet

A

Fruits and vegetables

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9
Q

Hyper tension trials

A

ALLHAT chlorthalidone, acei and ca blockers .. Alpha blockers were dropped due to CHF
SHEP trial low stroke rate chlorthalidone

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10
Q

Atenolol studies

A

Life study atenolol with lasartan
More strokes and death with atenolol
Ascot trial more deaths with atenolol than Norvasc

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11
Q

Accomplish trial

A

Amlodipine/ benazapril vs benazapril/hctz.. Amlodipine group did better and the study was stopped

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12
Q

Acei

A

30% increase in creatinine is ok
Reduces intra glomerular pressure
Adverse conditions
Hypovolemia and CHF bilateral renal stenosis

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13
Q

At2 receptor blockers

A

Not much better

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14
Q

Calcium blockers

A
Blacks diabetes elderly
Superior stroke reduction 
Diastolic dysfunction 
Metabolically neutral
BP lowering not effected by sodium or NSAIDs
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15
Q

Clonidine

A

Need bid dose
Rebound HTN
Depression

16
Q

Direct vasodilators

Hydralazine

A
Adjuvant 
Lupus 
Does not regress LVH
eDRF dependent 
Need to add diuretics
17
Q

HTN

A

Hypertensive urgencies no end organ damage
Hypertensive emergencies end organ damage
Labetalol
Nipride
Nicardipine

18
Q

Resistant HTN

A
Smoking
Non compliance 
Salt intake 
Obesity 
Alcohol 
Sleep apnea 
Pain,NSAIDs
19
Q

Pregnancy

A

BP should go down not up
No nipride
Labetalol , methyl dopa ca blockers
Don’t use acei and ARB also no atenolol acebutalol no hydralazine

20
Q

Black patients

A

Over all mortality in all races is dropping
Black men more likely to have mi
Black woman more likely to have HTN