Pulmonary Flashcards

0
Q

Obese patient HTN

A

Look for sleep apnea

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1
Q

Trousseau syndrome

A

Malignancy with recurrent PEs

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2
Q

Malignant HTN

A

Papilleda

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3
Q

Pulmonary hypertension

A

> 25 mm at rest

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4
Q

Pulmonary hypertension

A

Primary

Secondary

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5
Q

Eisenmenger PFO closure

A

Helps in some cases

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6
Q

Pulm HTN idiopathic

A

Autosomal dominant

Abnormal Bone marrow protein receptor

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7
Q

Drug induced pulm HTN

A

Aminorex
Fenfen
Amphetamine
Increases serotonin

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8
Q

Pm HTN associated with

A
Lupus
Scleroderma
HIV
Portal HTN
Eisenmenger 
Schistosomiasis
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9
Q

Venoocclusive

A
Male female 1:1
Genetic
Imminogenic
Bleomycin 
Diffuse occlusion of pulm veins
Severe pulm HTN pulm edema elevated LVEDP
Death in 2 years prostacyclins worsen
No Bosentan
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10
Q

Pulm HTN due to left heart disease

A

No prostacyclins

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11
Q

Pulm HTN due to hypoxia

A

Copd
ILD
Sleep apnea

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12
Q

Pulm veno occlusive

A

Make female 1:1
Severe pulm HTN pulm edema and elevated EDP

Death in 2 yrs
Prostacyclin may worsen the condition
No Bosentan

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13
Q

Chronic thromboembolic pulmonary hypertension

A
Progressive dyspnea
Chest pain
Exertional intolerance
Syncope
Pedal edema
Best test is VQ scan
Ct angiography 
Pulm angio
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14
Q

chronic thromboembolic pulm HTN

A

Peri op mortality 4%

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15
Q

Pulm HTN other causes

A

Splenectomy
Sarcoidosis
Dialysis

16
Q

Pulm HTN

A

Angina due to sub endo RV is bad sign
P2 wise split

VCR enlarged PA
Oligemic lung fields

RSVP =4x TRV2+RA pressure

17
Q

Pulm HTN tests

A
HIV 
Liver
ANA, ANCA.
,bnp
Sleep study
Exercise test 6min walk
18
Q

Pulm HTN

Right heart cath

A

Mean PAP >25 mm

Group 2 has high LVEDP over 15

19
Q

Pul HTN treatment

A
Group 1 IPAH no treatment 
Group 2 left heart treat CHF 
Group 3 hypoxemia
Group 4 thromboembolic anticoag and surgery
Group 5 underlying cause
20
Q

Pulm HTN respond to nitric oxide

A

Treat with ca blockers

21
Q

Pulm HTN no response to nitro up

A

Iloprost inhalation 6-9x a day
Flolan iv 1-4 weeks diarrhea flushing
Bosentan endothelial antagonist improved exercise hepato toxic
62.5 bid
Sildenafil improves exercise and oxygenation can be additive

22
Q

Pulm HTN

A

Atrial septatomy 15-20% mortality

Transplant

23
Q

PE

A
Mortality 30%
RV dysfunction 
High bnp
Pulm embolism severity index -pesi
Age>80,cancer, copd, high hr,low BP , low sat
0 point 1% mortality
One or more 10%
24
Q

PE risk

A

DVT
Surgery
Immobilization obesity
Smoking

25
Q

Symptoms

A

33% a symptomatic

26
Q

Wells criteria

A
DVT 3 points
No explanation 3 points
Tachycardia 1.5
Immobility surgery 1.5
H/o DVT 1.5
Hemoptysis 1
Cancer 1
Score 6 high prob 2 low prob
27
Q

PE

A

Tropinin high 30-50%

Normal D dimer in low to moderate probability excludes PE

28
Q

PE echo

A

30-40% abnormal

Decrease RV function and increase RV size

29
Q

Warfarin induced skin necrosis

A

In protein C deficiency

30
Q

First PE

3-6 mos provoked

A

Unprovoked and recurrent indefinite Coumadin therapy

31
Q

Thrombolysis PE

A
Severe hypoxemia 
Large PE 
RV dysfunction 
Free floating thrombus
PFO
32
Q

Cpap

A
26% at risk
Ahi total number of apnea and hypoapnea per hour
Mild 5-15
Moderate 15-30
Severe >30