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Cardiology > Trials > Flashcards

Trials Flashcards

0
Q

Wiscops

A

All statins out come 23% better

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1
Q

TNT

A

High and low dose Lipitor high dose better

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2
Q

Ascot

A

20 mg Lipitor

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3
Q

Hps

A

Simvastatin study

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4
Q

Prove it

A

Pravachol inferior to Lipitor

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5
Q

Framingham risk

A 
Age
Gender
Cholesterol 
HDL
Smoking
HTN 
Treating the HTN 
It under represents women and under estimates younger people risk
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6
Q

Asvd risk

A

CRP>2
Family history
ABI400

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7
Q

Courage trial

A

Pci superior to medical with angina

Excludes low EF recent pci and ongoing cp

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8
Q

Timac trial

A

High risk early intervention

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9
Q

Bari 2D

A

OMT and pci or CABG same for death

Aggressive diabetic no help

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10
Q

All hat

A

Chlorthalidone ace and ca blockers all equal.

Alpha blockers were dropped due to CHF

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11
Q

Accomplish

A

Norvasc/ benazapril vs benazapril/ hctz

Stopped as Norvasc limb was superior

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12
Q

Shep

A

Chlorthalidone less strokes

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13
Q

Athena study

Pallas study

A

Athena Dronedarone is superior to rate control
Less stroke
Pallas drone done increase death in CHF and permanent afib

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14
Q

Cogent trial

A

Plavix and omeprazole no difference

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15
Q

Comet study

A

Coreg reduces the effectiveness of dibutamine

Lopressor dies it only partially

16
Q

Poise study

A

Routine use if beta blockers increase mortality

17
Q

Stitch trial

A

People with low EF and cad
CABG did not reduce mortality
Only Lima to lad helpful
Viability useless

18
Q

Vheft

A

Blacks and CHF

Do better with hydralazine and nitro

19
Q

Rales and epsesius

A

CHF trial rales about aldactone
Epsesius about eplerimone
Both reduce death by30% but start acei first

20
Q

Plato

A

Ticagrelor better than plavix

21
Q

Triton timi38

A

Prasugrel better than plavix

22
Q

Freedom

CABG vs DES in DM

A 
Higher death CVA mi 
14% mi in pci vs 6% CABG 
Stroke is higher with CABG 
Higher repeat with pci 
With low scores they are identical
23
Q

Syntax

A

1year higher repeat vascularization for pci
Pci was reasonable in unprotected left main in low syntax scores
Over 22 CABG over pci
Stokes higher low syntax
Over 22 higher tia and mi in pci
Over all MACCE higher for pci

24
Q

Val heft valsartan CHF

A

Charm candisartan CHF

25
Q

Courage trial

A

OMT vs pci and OMT

Slight increase in death and mi with OMT
More Angina free in pci group

26
Q

Acuity

A

Angio max better than ufa and 2b3a

27
Q

Horizons

A

TVR high for des compared to BMS

28
Q

Companion

A

CRT improves survival by 30%

29
Q

Vt nsvt icd survival

A

Must

30
Q

Oat trial

A

No benefit on CTO vs medical therapy

31
Q

Isis2

A

Asa benifit

32
Q

Hot trial

A

Angio max and UFH

Angio max higher MACCE more bleeding

Cardiology (18 decks)

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