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Top 100 Drugs (Brand-Generic) > VaccinaTiONS > Flashcards

VaccinaTiONS Flashcards

1
Q

Afluria

Fluarix

FluLaval

Fluvirin

Fluzone

A

Influenza virus

  • Recommended for ages > 6mo ANNUALLY
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2
Q

Fluzone

A

Thimerosal-FREE

6 MO and OLDER

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3
Q

Flucelvax

A

Influenza

Flucelvax (> 18 yrs)

Flucelvax Quadrivalent (> 4 yrs)
———————————————

Cell-Culture-based

Starter strain originally grown in EGG. Minuscule amounts of ovalbumin; the package insert DOES NOT mention EGG allergy as a contraindication or precaution

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4
Q

Flubok

A

(18-49 YRS)

  • Produced with INSECT VIRUS AND RECOMBINANT DNA
  • DOESNT USE EGG IN ITS PRODUCT
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5
Q

FluMIST

A

Quadrivalent, LiVE attenuated

  • NASAL SPRAY
  • Formulation changes ANNUALLY

(2-49 yrs OLD)

  • *PRESERVATIVE FREE**
  • *Thimerosal FREE**
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6
Q

Fluzone HD

A

SENIORS > 65 y/o

  • HIGH DOSE

4x’s as much ANTiGEN as STANDARD adult vaccine to help BOOST iMMUNITY.

  • 60mcg of EAch virus strain (INSTEAD of 15mcg w/ STANDARD)
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7
Q

Fluzone INTRADERMAL

A

(18-64 y/o)

  • AVOIDS POSSIBLE MUSCLE SORENESS
  • PRESERVATIVE FREE
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8
Q

Afluria

A

NEEDLE-FREE formulation

  • (18-64 Y/O)
  • JET INJECTOR
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9
Q

Fluad

A

Adjuvanted TRIVALENT vaccine

> 65 Y/O

ADJUVANT- enhances bodys IMMUNE RESPONSE

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10
Q

PneumoVAX

  • PPSV23
A

Dose: > 2 Y/O

0.5 mL IM/SUBQ

Indication: children > 2 yo

Who should receive:?

> 65yo (5 years after last dose)

Smokers/Asthma/ COPD

chronic diseases (CHF; DM; liver/ alcoholism)

Cochlear implants

CSF LEAKS

IMMUNOCOMP: HIV/ asplenia/ sickle cell

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11
Q

Who should receive PNEUMOCOCCAL VACCINE??

A

> 65 Y/O

  • Smokers > 18 Y/O
  • Asthma/ COPD
  • CHRONIC DISEASE
    (CHF, DM, LIVER, Alcoholism)
  • Cochlear IMPLANT
  • CSF LEAK
  • Immunocompromised
  • asplenia**
  • sickle cell (Revaccinated)

** Asplenic/ immuno-comp patients < 65 Y/O should be revaccinated once 5 yrs after the initial dose, and AGAIN after 65 y/O (5 yrs apart) (TOTAL OF 3 DOSES)**

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12
Q

PREVNAR 13

A

Pneumococcal 13- VALENT

  • Prevention of PNA, Meningitis, OTITIS MEDIA
  • conjugated to DIPTHERIA

Indication: > 6 wks; high-risk pts; > 65 yo

SHAKE VIGOROUSLY PRIOR TO ADMIN

Peds dose: 2 mo, 4MO, 6MO, 1 yeAr(4 TOTAL DOSE)

IM ONLY**

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13
Q

Pneumococcal DUAL VACCINATION

A
  • Asplenia, SC, CSF Leak, Cochlear IMPLANT, or IMMUNO-COMP (HIV, ESRD, CANCER)

—> If Naive: Give PCV-13 followed by PPSV23 > 8 wks LATER

—> If vaccinated 1st w/ PPSV23 in < 19 Y/O pt, give PCV-13, 8 WEEKS later

—> if vaccinated 1st w/ PPSV23 in > 19 g/O pt, then give single DOSE of PCV13 > 1 yr LATER

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14
Q

Engerix-B; RecombiVAX HB (L/C)

A

Hep B

  • IM (NOT LIVE)

** Refrigerate**

May interchange products

CONTRAINDICATED IN YEAST ALLERGY!!

Dose: THREE DOSES!!

**4 wks between 1-2 doses

8 wks between 2-3

6 wks between 1-3**

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15
Q

Who should get HEP-B VACCINATION?

A
  • Health care WORKERS
  • IV drug users, inmates, HIV PTS, CHRONIC LIVER Dx
  • UNVACCINATED KIDS
  • HEMODIALYSIS
  • sexually ACTIVE (>1 partner in 6mo; M2M, STD TREATMENT)
  • DIABETES (< 60 yo; 19-59)
  • ALL NEONATES BEFORE LEAVING HOSPITAL

CONTRAINDICATED IN YEAST ALLERGY

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16
Q

Infants born w/ HEPB and people exposed should receive what?

A

HBIG (Hepatitis B immune globulin)

Hep B vaccine

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17
Q

HAVRIX; Vaqta

A

HEP-A vaccine

Trans: FECAL/ ORAL

DOSE: TWO DOSES

ATLEAST 6 months BETWEEN DOSES

Admin: IM

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18
Q

Who should help HAVRIX VACCINE?

A

> 12-23 MONTHS Y/O

TRAVELING OUTSIDE US

  • Chronic Liver disease
  • IVDA
  • HIV pts
  • M2M
  • clotting factor disorders
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19
Q

Tetanus; Diphtheria; Pertussis

A

Tetanus - Clostridium tetani
(RUSTY NAIL; LOCK JAW; MS)

  • Tetanus IMMUNOGLOBIN (TIG)
    ————————————————-

Diphtheria - Corneybacterium Diphtheriae

 - Throat and nasal passage ————————————————-

Pertussis - Bordetella Pertussis

  - Whooping cough (High Pitch)
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20
Q

DTaP

A

Tetanus/ Diphtheri/ Pertussis

  • ALL infants, NOT CHD > 7 Y/o

Dose: 0.5mL IM: 2,4,6,18 months PLUS

                         4-6 yrs (5 doses)

**BOOSTER Tdap should be given at 11-12 yrs who have completed a childhood DTaP

  • CAPITAL LETTERS MEAN THAT THE VACCINE CONTAINS A LARGER DOSE OF ANTIGENS
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21
Q

Td

A

Tetanus toxoid

  • For pts previously NOT immunized
  • BOOSTER DOSE EVERY 10 yrs

(ACIP PREFERS Tdap)

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22
Q

DAPTACEL

A

DTaP
(Diphtheria/ Tetanus/ acellular Pertussis)

KIDS: 6 WEEKS —-> 6 YEARS

  • PRIOR TO 7th BIRTHDAY
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23
Q

ADACEL/ Boostrix

A

Tdap (0.5mL IM) - Deltoid

Indication: ACTIVE BOOSTER

ADULTS —-> 11-64 y/o

> 65 y/o who have CLOSE CONTACT W/ children should receive a ONE-TIME dose to PROTECT INFANTS

  • Pregnant women in 3rd TRIMESTER
  • Active BOOSTER is needed because immunity CHILDHOOD vaccine WEARS OFF IN 5-10 yrs
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24
Q

DTaP is contraindicated in which patients??

A
  • Encephalopathy w/ PRIOR DTaP
    ————————————————
  • Use w/ CAUTION in kids w/ progressive or unstable NEUROLOGIC PROBLEMS*
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25
MMR | Measles, Mumps, Rubella
- LIVE VACCINE - FREEZE OR REFRIGERATE - SUBQ - Dose: 2 SERIES. 1 yr old + 5 yrs old —————————————————- Measles: Koplik’s spots (rash around mouth), cough, Fever Mumps: Salivary gland enlargement (PAINFUL) Rubella: German measles. Cause abortion/still birth/ birth defects
26
Who should receive MMR?
- Health care workers, College students, International travelers - All women of child bearing age, but NOT DURING PREGNANCY!!
27
MMR CONTRAINDICATIONS
- Pregnancy - ImmunoCOMP (CD4 < 200) - **neomycin allergy, gelatin** - SEVERE THROMBOCYTOPENIA (Measles)
28
Proquad
MMR + Varicella - STORE IN FREEZER(MUST) - Do not FREEZE diluent Dose: 2 SERIES (1 yr + 5 yrs old)
29
Varivax
Varicella * LIVE VACCINES* Dose: 2 SERIES (1 yr + 5 yrs) Admin: SUBQ Storage: FREEZER
30
Varizig
Varicella Zoster Immune Globulin - Decrease severity of chk pox when given FOUR DAYS AFTER EXPOSURE
31
IPV(IPOL)
POLIO - Breathing muscle PARALYSIS *OPV LIVE not available in USA* ————————————————- - Use in infants/ chd < 5 yrs old - * NOT RECOMMENDED FOT ADULTS UNLESS TRAVELING TO ENDEMIC AREAS* Dose: 0.5mL IM/SUBQ @ 2,4,6-18 m and 4th Dose at 4-6 yrs old (FOUR TOTAL DOSES) ———————————————— Contains trace of: streptomycin, neomycin, polymyxin B Kinrix/ Quadracel: DTaP- Polio combo - IM children 4-6 yrs old: 0.5mL SINGLE DOSE
32
Kinrix/ Quadracel
DTaP- Polio combo Dose: 0.5mL as SINGLE DOSE
33
ActiHIB; Hiberix; PedvaxHIB
H. influenza type B (Hib) Admin: (2 mo- 5 y/o) - ALL CHD < 5 y/o Dose: 0.5mL @ 2,4,6, 12-18 mo (4 DOSES) ADULTS W/ Asplenia, Sickle Cell, stem cell transplant, planned splenectomy - MENINGITIS - Pneumonia - Epiglottitis
34
Menactra; MenVEO (MCV—4)
Conjugated MENINGOCOCCAL - QUADRIVALENT Menactra——> 9mo-55yo** MenVEO—> 2mo-55yo** ——————————————— Dose: 0.5mL IM/SQ (MCV-4 given IM) **First DOSE 11-12YO + BOOSTER @ 16YO**
35
MenoMune
Polysaccharide Meningococcal - SUBCUTANEOUSLY, even THOUGH IT IS NOT LIVE** > 2YO
36
Trumenba; Bexsero
MENINGITIS B - **HIGH RISK PTS** (asplenia; sickle cell) - **NOT A REPLACEMENT FOR MENACTRA OR MENVEO**
37
Pneumococcal Risk Average risk: >65 yo with no conditions
PCV13 followed by PPSV23 ONE yr LATER
38
Pneumococcal Risk Elevated Risk: chronic HEART DISEASE, chronic LUNG DISEASE (COPD, emphysema, asthma), cigarette smoking, DIABETES, alcoholism, CHRONIC LIVER DISEASE, Cirrhosis, Cigarette smoking
PPSV23
39
Pneumococcal risk: High Risk: Cerebrospinal fluid leak Cochlear Implant
PCV13, eight weeks PPSV23
40
Pneumococcal RISK Very high risk: IMMUNOCOMPROMISED (HIV, RENAL FAILURE, Functional ASPLENIA (sickle-cell) CANCER PATIENTS
PCV 13 followed by PPSV23 8 WEEKS later followed by PPSV23 5 years LATER
41
Heplisav B
Hepatitis B VACCINE >18 YEARS OLD TWO DOSES OF 0.5mL IM ONE MONTH APART
42
Who gets meninococcal VACCINE
1. All adults aged 11-18 yrs 2. ^ Risk children First dose 11-12 y/o + booster at 16 y/o High risk: asplenia, sickle cell, HIV, taking eculizumab (solaris), traveling to endemic area. REPEAT IN 5 years for at risk patients - College freshman living in dorms - U.S Military - Travelers to endemic areas; Hajj pilgrimage to MECCA; - Patients with damaged spleen or splenectomy - HIV infection - evulizumab use (Solaris) - Laboratory personnel who are EXPOSED - Exposure to meningitis during an outbreak **REPEAT IN 5 YEARS IF REMAINING AT RISK**
43
Human papillomavirus 9-valent vaccine | GARDASIL 9
Cervical cancer is a common female cancer world-wide Gardasil 9: 9-valent HPV vaccine covers - 6,11,16,18, 31,33,45,52,58 **INDICATED FOR FEMALES AND MALES for the prevention of cervical cancer/ anal cancer/ genital warts**** - FEMALES/ MALES AGE 9-45 y/o - Starting at 11-12 y/o - IM Cervical and anal cancers caused by: all except 6/11 Genital warts are caused bu: **6; 11**
44
Zostavax
LIVE- SUBQ ZOSTAVAX FDA APPROVED > 50 y/o CDC Recommends it for patients > 60 Contraindications 1) Gelatin or neomycin allergy 2) Immunocomp (inc. STEROIDS) FREEZER LIKE VARICELLA
45
Shingrix
NOT LIVE - 2 DOSES (2nd dose in 2-6 MO) - REFRIGERATE Indicated for > 50yo to PREVENT SHINGLES administer immediately upon reconstitution or STORE refrigerated and use within 6 HOURS
46
Which vaccines are oral?
- Vivotif Berna | - Rotavirus
47
Which vaccines are IM or SC?
- Polio | - Pneumovax
48
Which vaccines are given SC ONLY?
- Varicella - MMR/MMRV - Zostavax - Yellow fever
49
Rotavirus vaccine for infants
Rotarix (LIVE): 2 DOSES -started at 6 WEEKS; second dose 1 MONTH later RotaTeq (LIVE; ORAL): 3 DOSES; given at 2,4,6 MONTHS
50
Ixiaro
Japanese encephalitis vaccine -2 DOSES IM 28 days apart > 2 months old **JE-VC is NOT recommended for short-term travelers whose visit will be restricted to urban areas**
51
Typhim Vi
Typhoid Vaccine - KILLED (inactivated) - IM x 1 (0.5mL 2 wks prior)
52
VivoTIF Berna
Typhoid Vaccine - **ORAL** 4 DOSES EOD - For patients > 6 y/o - 1 wk prior to exposure * *REFRIGERATE CAPSULES** * *AVOID ALCOHOL**
53
Yellow Fever
-South America & Africa - LIVE - 0.5mL SC for > 9 MO -------------------------------- Cautions/Contraindications: Egg allergy & Pregnant women, immunosuppressed, or **THYMUS** disease
54
Rabvert; Imovax Rabies
-For caver's, bat handlers, and veterinarians IM: 3 doses, 1 mL on days 0,7,21,28.
55
Post exposure PPX for rabies?
- Give Rabies Immune Globulin (HRIG) * kedRAB* | - Vaccinate w/ 5 doses over 28 days
56
TwinRix
Hep A + Hep B | > 18 y/o
57
Proquad
MMR + Varicella | **FREEZER ONLY**
58
Kinrix / Quadracel
DTaP + IPV | -IM 4-6 y/o
59
PediaRix
DTaP + Hepatitis B + IPV
60
Pentacel
DTaP + IPV + Hib (H.influ)
61
Contraindicated in pregnancy?
- MMR - Varicella - Zostavax - Vivotif BERNA - Meningococcal (ONLY one thats NOT live)
62
Thimerosal (preservative)
Influenza (Fluzone is thimerosal FREE)
63
Contraindicated in AIDS (not HIV)
``` Varicella** (HIV) can give MMR** (HIV) can give Zoster Flumist Yellow Fever ** (HIV) Cn gv VivoTIF Berna ```
64
Use with caution in Neomycin allergy
MMR Varicella Zostavax Polio
65
Vaccines prepared in Egg?
Yellow Fever
66
Post-splenectomy/ Asplenia/ Sickle cell disease
Capsular polysaccharide bacteria are cleared by the spleen - Streptococcus PNA - H. flu (Hib) - Neisseria meningitidis
67
What immunizations for TRAVELORS?
YELLOW BOOK - Hep A - Hep B - Meningococcal - Typhoid - Yellow fever - Japanese encephalitis (Ixiaro)

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