Asthma/COPD Flashcards by hannibal britton

Ventolin HFA, proventil HFA, Proair HFA, ProAir Respiclick, VoSpire ER

ALBUTEROL

MDI, DPI, Tablet, Syrup, solution (NEB)

Respiclick > 12 yo
0.5% soln > 2 yo

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VoSpire ER

Albuterol XL tablets

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XOPENEX

Levalbuterol

OPEN FOIL - 2 weeks exp

DRUG OUT OF FOIL - 1 week exp

HFA : 4+ YO

NEB: 6+ YO

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QVAR HFA

Beclomethasone (corticosteroid)

MDI : 5+ YO
NASAL SPRAY: ?

DONT NEED SPACER; smaller particle size

DONT NEED TO SHAKE; soln

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VANCENASE

BECONASE

QNASL

Beclomethasone (corticosteroid)

Nasal spray (RX)

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PULMICORT

BUDESONIDE (corticosteroids)

Pulmicort Flexhaler (DPI): 6+ YO

Pulmicort Respules (NEB): 12+ MONTHS

DOC in PREGNANCY

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AEROSPAN

Flunisolide (corticosteroid)

MDI

Comes with built-in SPACER

6+ YO

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Asmanex Twisthaler

Mometasone (corticosteroid)

1-2QPM (only ONCE A DAY, ICS)

DPI/MDI

5+ YO

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Flovent HFA

Fluticasone

MDI/DPI/ NASAL

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Arnuity ELLIPTA

ARMONAIR

Fluticasone DPI

12+ YO

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FLONASE / VERAMYST

Fluticasone : (NASAL)

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ALVESCO

Ciclesonide (corticosteroid)

MDI/ NASAL

1-2 puff BID

12+ YO

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Omnaris / Zetonna

Ciclesonide (corticosteroid)

NASAL

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Oral prednisone

DOSE & DURATION

40-60mg qd x3-10 days

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Medrol DOSE PACK

Methylprednisolone

Taper 24mg to 0mg PO for 6 days

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Corticosteroids

General INFO

SE: oral candidiasis
Dysphonia (difficulty speaking)
Cough

Notes: RINSE MOUTH & use a SPACER
to prevent oral candidiasis

FIRST-LINE against PERSISTENT asthma

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SERVENT

Salmeterol (LABA)

4+ YO

Good for 6 WEEKS after opening

COMBO: ADVAIR (salmeterol + fluticasone) is good for ONLY 30 DAYS

FORADIL

Formoterol (LABA)

5+ YO

REFRIGERATE CAPSULE

DPI: Good for 4 MONTHS

Combos: (ICS + LABA)

Symbicort: (formoterol + budesonide)

DULERA: (formoterol + mometasone)

Methylxanthines

THEOPHYLLINE

300-400mg/day (MAX 900mg)

used in INFANTS up to 6 WEEKS old

LEVEL: 5-15mcg

> 15 : toxicity
30 : SVT
50 : SEIZURE

AccoLATE

ZafirluKAST (Anti-leukotrienes)

20mg BID

5+ YO: 10mg BID

EMPTY STOMACH

SINGuLAR

MonteluKAST (Anti-leukotriene)

4,5,10mg DAILY

CHILDREN 1+ YO (4-5mg QD)

SE: * Flu-like symptoms**

   * Restlessness**
   * watch for mood/behavioral changes

Do not mix with any LIQUIDS other than FORMULA & Breast-MILK

ZyFLO CR

Zileuton

600mg BID

12+ YO*
ELEVATED ALT* monitor before treatment

XOLAIR

Omalizumab (IgG1k monoclonal AB)

SQ every 2-4 WEEKS BASED ON

1) BODY WEIGHT
2) serum IgE level

SE: MALIGNANCIES
Increase risk of CVD & Cerebrovascular & viral upper resp infection

BBW: * ANAPHYLAXIS*

6+ asthma/ 12+ chronic hives

FOR USE WHEN SYMPTOMS NOT CONTROLLED WITH ICS

Helps with ALLERGY RELATed Asthma

CinQAIR

ReslizUMAB

Add on for severe asthma w/ eosinophillic phenotype

IL-5 Receptor antagonist

3mg Q4WEEKS

Compatible: NS

BBW: anaphylaxis

Risk factors for COPD

``` Smoking Age Existing impaired lung fx Occupation Alpha1-anti trypsin deficiency ```

AnticholinERGIC GENERAL info

SE: HA, dizziness, DRY MOUTH, URINARY RETENTION, BLURRY vision Caution: - glaucoma (worsening of narrow angle glaucoma) - BPH

AtroVENT

Ipratropium (anticholinERGIC) HFA 2-3 puff *QID* Contraindication: * PeaNUT allergy *

CombiVENT

Albuterol + Ipratropium RESPIMAT 1 spray *QID* Exp: 3 MONTHS *NOT* contraindicated in PEANUT AND SOYBEAN allergy SHAKING not REQ

DuoNEB

Albuterol + IpratroPIUM (NEBULIZER) Same as combivent except for nebulizer 1 unit dose nebuliZed *QID* prn, max 6 doses/day

SpiRIVA

Tiotropium (anticholinergic) Handihaler (DPI) QD - Cap Respimat (SMI) Asthma/Copd 12+ yrs

TuDORZA Pressair

Aclidinium (anticholinergic) 1 DPI BID

InCRUSE Ellipta

Umeclidinium (anticholinergic) Once DAILY

StriVERDI Respimat

OlodaTEROL (LABA) Once DAILY

ArCAPTA

IndaCATEROL (LABA) 75mcg Capsule DAILY

PerFOROmist

FORmoterol (LABA: NEBulized soln) Exp: 6 weeks at ROOM TEmp *REFRIGERATE* 1 vial BID

BroVANA

ArFORmoterol (LABA: NEBulized) 1 vial BID ROOM TEMP: up to 6 WEEKS *Refrigerate*

SymBICORT

FORmoterol + BUDesonide (ICS+ LABA) TWICE DAILY (BID) Exp : 90 DAYS

AdVAIR

SALmeterol + FLUticasone (ICS+LABA) Advair Diskus: 4+ yrs Advair HFA: 12+ yrs AirDUO respiclick : 12+ yrs Exp: 30 days

BREO ELLipta

VILANterol + Fluticasone (ICS+LABA) QD: Once DAILY Exp: 6 WEEKS

ANORO ELLipta

Umeclinidium + VilANTerol (Anticholinergic + LABA) 1 inh DPI QD: Once daily Exp: 6 WEEKS

Stiolto Respimat

OloDATEROL + Tiotropium (anticholinergic/ LABA) 2 puff QD: DAILY

DALiresp

Roflumilast (PDE-4 inhibitor) 500mcg PO DAILY SE: *Psychiatric events (SUICIDAL) * WEIGHT loss CONTRAINDICATED IN LIVER IMPAIRMENT CYP4A4 & CYP1A2 substrate hence avoid with strong INDUCERS will decrease levels