Anticoag

Question 1

Fragmin

Answer 1

Dalterparin

PPX: 2500-5000U SC QD

LMWH

Xa inhibitor

Question 2

LOVENOX

Answer 2

ENOXAPARIN

Adjust in CrCL < 30

LMWH

Xa inhibitor

Question 3

Argatroban

Answer 3

IV

Elevate INR

CAN Be used for HIT

LIVER

IIa inhibitor

Question 4

REOPRO

Answer 4

Abciximab

GP IIb/IIIa inhibitor (ANTI-PLATLET)

NO RENAL DOSE ADJUSTING

Question 5

AGGRASTAT

Answer 5

Tirofiban

GP IIb/IIIa inhibitor

Crcl < 60, adjust dose
Crcl < 30, reduce dose by 50%

Question 6

INTEGRILLIN

Answer 6

Eptifibatide

IIb/IIIa inhibitor

Crcl < 50, dose adjust

SHORT HALF LIFE

Question 7

PLETAL

Answer 7

Cilostazol

ADP blockers

p2y12 inhibitors

Use for: INTERMITTENT CLAUDICATION

Question 8

PLAVIX

Answer 8

Clopidogrel

IRREVERSIBLE inhibitor of p2y12 ADP

D/C 5 days before surgery

Question 9

EFFIENT

Answer 9

PRASUGREL

P2y12 ADP inhibitor

More bleeding than clopidogrel

DC 5 days prior to surgery

Question 10

BRILLINTA

Answer 10

Ticagrelor

REVERSIBLE inhibitor of p2y12 ADP

Rapid onset

NOT A PRODRUG

Uric acid increase
Increase simvastatin and lovastatin

BBW: asa above 100mg reduces effectiveness

Question 11

KENGREAL

Answer 11

Cangrelor IV ONLY

RAPID ONSET
SHORT HALF LIFE

Question 12

DURLAZA

Answer 12

ASPIRIN

EXTENDED RELEASE

Question 13

PERSANTINE

Answer 13

Dypyridamole

REVERSIBLE inhibitor of platlet aggregation

VASODILATOR

QID w/ water 1 hour before meals

Question 14

AGGRENOX

Answer 14

Aspirin + dipyridamole

1 cap BID

Question 15

ANGIOMAX

Answer 15

Bivalirudin IV

Renal category B

IIa (Thrombin) inhibitor

Question 16

IPRIVASK

Answer 16

Desirudin SC

15mg SC Q12H

IIa (Thrombin) inhibitor

Question 17

PRADAXA

Answer 17

Dabigatran

IIa (Thrombin) inhibitor

Question 18

ZONTIVITY

Answer 18

Vorapaxar

PAR-1 inhibitor

2.08 mg QD

W/ low-dose asa and/ or clopidogrel for secondary prevention of post-MI