Uworld - Renal VIII

Question 1

ACE I effect on GFR

Answer 1

block efferent arteriole vasoconstriction

rise in serum Cr - reduced FF

Question 2

selective albuminuria

Answer 2

minimal change disease

loss of negatively charged molecules of GBM - albumin lost more

Question 3

tx post-op urinary retention

Answer 3

muscarinic agonist - bethanechol (stimulate detrusor)
alpha1 blocker (less sphincter contraction)

Question 4

round polygonal cells clear cytoplasm

Answer 4

renal cell carcinoma - clear cell

glycogen and lipid packing

Question 5

karyorrhexis

Answer 5

occurs in apoptosis

Question 6

prognosis of PSGN

Answer 6

95% children recover
60% adults recover

age is important prognostic factor

Question 7

HUS organisms

Answer 7

E. Coli O157:H7

shigella

Question 8

HUS presentation

Answer 8

bloody diarrhea
hemolytic anemia and schistocytes
thrombocytopenia
acute kidney injury

Question 9

compensation in nephrotic syndrome

Answer 9

loss of protein - increased cholesterol production

-maltese crosses

Question 10

gross hematuria elderly man, hx smoking, work with rubber, plastic, dye

Answer 10

transitional cell carcinoma of bladder

Question 11

staghorn calculi

Answer 11

struvite stones
-Mg triple phosphate

with proteus infection

Question 12

stones with proteus infection

Answer 12

struvite

Question 13

digoxin adverse

Answer 13

cleared by kidney - get age related insufficiency