Uworld Practice Test 1

Question 1

ARDS is caused by injury to?

Answer 1

Endothelial Lining

Question 2

Paget’s disease of the bone is associated with?

Answer 2

Osteosarcoma

Question 3

Lump in the throat is?

Answer 3

Globus hystericus

Question 4

What vitamin is tetratogenic?

Answer 4

vitamin A

Question 5

Oseltamivir (Tamiflu) MOA? Use?

Answer 5

MOA: inhibits neuroamindase of influenza A and B
Use: Early treatment and prevention of influenza

Question 6

Cells varying in length and time show?

Answer 6

Posttranslational modification

Question 7

Fragmentation in multiples of 180 base pairs. What is this called?

Answer 7

DNA Laddering

Question 8

Where is DNA laddering found?

Answer 8

During Karrhyrexis in Apoptotic cells

Question 9

Why is DNA laddering used?

Answer 9

To distinguish between apoptotic cells and necrotic cells

Question 10

Physgiostigimine fights?

Answer 10

Atropine

Question 11

Benzodiazpine AE?

Answer 11

confusion

Question 12

When a genetic mutation is identified in the offspring but not the parents?

Answer 12

Germline Mosaicism

Question 13

DM patients should always do what every day?

Answer 13

Foot Ulcer

Question 14

IL-1, TNF-alpha, IL-6 is primarily produced by? What are they produced in response to?

Answer 14

Mononuclear phagocytes/Marcrophages

Inflammation

Question 15

What is Ca2+ dependent and connects intercellular adhesions?

Answer 15

Cadherins

Question 16

Low pH of udodenal content triggers release of?

Answer 16

Bicarb

Question 17

Posterior displacement of the tibia? What artery is affected?

Answer 17

popliteal artery

Question 18

Foul Smelling Discharge after a vaginal delivery? Agent?

Answer 18

Endometritis

Bacteriodes

Question 19

Person channels socially unacceptable impulses to acceptable impulses (like channeling abuse to basketball)

Answer 19

Sublimation

Question 20

Tyrosine Kinase auto?

Answer 20

phosphorylates and dimerizes

Question 21

Physician repeats what patient has told him? Defense mechanism?

Answer 21

Reflection

Question 22

Physician encourages patient to talk more about a technique?

Answer 22

facilitation

Question 23

Individual attributes thoughts and feelings to another person

Answer 23

projection

Question 24

Headache, chronic nasal discharge and atrophic septum?

Answer 24

Cocaine absuer

Question 25

Heminephrectomy changes GFR from what to what?

Answer 25

50%=>80%

Question 26

When she pushes against a wall with outstreched arms, there is prominence of the right scapular angle? What nerve and muscle is involved?

Answer 26

Winged Scapula SALT (serratus anterior and Long thoracic n.)

Question 27

ATSD vs PTSD Difference?

Answer 27

>4 weeks PTSD

Question 28

Schizophrenia symptoms?

Answer 28

Delusions, hallucinations, disorganized speech or negative symptoms

Question 29

Schizophrenic symptoms for 1-6 months

Answer 29

Schizophreniform symptoms

Question 30

Schizophrenic symptoms for >6 months

Answer 30

Schizophrenia

Question 31

Schizophrenic symptoms

Answer 31

Brief Psychotic episodes

Question 32

Relative Risk?

Answer 32

Exposed Risk/Unexposed Risk

Question 33

Number needed to treat is opposite of the?

Answer 33

absolute risk reduction value

Question 34

Absolute Risk Reduction?

Answer 34

Percentage of mortality in Conventional-Percentage of mortality in Novel

Question 35

Headache, altered level of consciousness and increased signalling in the temporal lobe?

Answer 35

Encephalitis

Question 36

MCC of viral Encephalitis?

Answer 36

HSV

Question 37

MC Porphyria?

Answer 37

Porphyria cutanea tarda

Question 38

Acute Intermittent Porphyria, enzyme and accumulation?

Answer 38

Hydroxymethylbilane (HMB) synthase | Porphobilinogen

Question 39

Porphyria Cutanea Tarda, enzyme and accumulation?

Answer 39

URO decarboxylase | Uroporphyrinogen

Question 40

What diseases have Anticipation?

Answer 40

Trinucleotide repeat diseases

Question 41

Recurrent hemathroses?

Answer 41

Hemophilia

Question 42

Hemophilia Genetics?

Answer 42

X-linked

Question 43

Exudate vs transudate fluid

Answer 43

Exudate | Protein>0.5 and Pleural LDH>0.6

Question 44

Hemolysis in buffered salt solutions?

Answer 44

Osmotic Fragility

Question 45

Hereditary Sphercytosis Labs?

Answer 45

Increased MCHC, acidified glycerol test | abnormal eosin 5

Question 46

Complications of hereditary sphercytosis

Answer 46

Gallstones and aplastic anemia

Question 47

An elderly alcholic with Shock-like sensation that radiates to the feet and neck, what vitamin def.?

Answer 47

B12

Question 48

B12 vs Folate deficiency?

Answer 48

Folate does not induce neurologic symptoms

Question 49

A young patient with difficulty chewing, seeing, What is wrong in this patient?

Answer 49

MG

Question 50

Which is more common Hyperplastic Tissue vs Thymoma?

Answer 50

Hyperplastic Tissue

Question 51

How many genes need to deleted in tumor supressor genes? What is this phenomenon called? Examples?

Answer 51

2 2 hit hypothesis Retinoblastoma

Question 52

Recurrent Fungal or Viral infections suggest problems in?

Answer 52

T-Cell lymphocyte

Question 53

Digeorge Syndrome is the failure of the development of?

Answer 53

3rd and 4th pouch

Question 54

Metabolics associated with DKA?

Answer 54

Metabolic Acidosis, Hyperkalemia, Hyperglycemia, Hyperammoniemia, Hyponatremia

Question 55

In pheochromocytoma, what drug should you use?

Answer 55

Phenoxybenzamine