Uworld Practice Test 1 Flashcards
ARDS is caused by injury to?
Endothelial Lining
Paget’s disease of the bone is associated with?
Osteosarcoma
Lump in the throat is?
Globus hystericus
What vitamin is tetratogenic?
vitamin A
Oseltamivir (Tamiflu) MOA? Use?
MOA: inhibits neuroamindase of influenza A and B
Use: Early treatment and prevention of influenza
Cells varying in length and time show?
Posttranslational modification
Fragmentation in multiples of 180 base pairs. What is this called?
DNA Laddering
Where is DNA laddering found?
During Karrhyrexis in Apoptotic cells
Why is DNA laddering used?
To distinguish between apoptotic cells and necrotic cells
Physgiostigimine fights?
Atropine
Benzodiazpine AE?
confusion
When a genetic mutation is identified in the offspring but not the parents?
Germline Mosaicism
DM patients should always do what every day?
Foot Ulcer
IL-1, TNF-alpha, IL-6 is primarily produced by? What are they produced in response to?
Mononuclear phagocytes/Marcrophages
Inflammation
What is Ca2+ dependent and connects intercellular adhesions?
Cadherins
Low pH of udodenal content triggers release of?
Bicarb
Posterior displacement of the tibia? What artery is affected?
popliteal artery
Foul Smelling Discharge after a vaginal delivery? Agent?
Endometritis
Bacteriodes
Person channels socially unacceptable impulses to acceptable impulses (like channeling abuse to basketball)
Sublimation
Tyrosine Kinase auto?
phosphorylates and dimerizes
Physician repeats what patient has told him? Defense mechanism?
Reflection
Physician encourages patient to talk more about a technique?
facilitation
Individual attributes thoughts and feelings to another person
projection
Headache, chronic nasal discharge and atrophic septum?
Cocaine absuer
Heminephrectomy changes GFR from what to what?
50%=>80%
When she pushes against a wall with outstreched arms, there is prominence of the right scapular angle? What nerve and muscle is involved?
Winged Scapula
SALT
(serratus anterior and Long thoracic n.)
ATSD vs PTSD Difference?
> 4 weeks PTSD
Schizophrenia symptoms?
Delusions, hallucinations, disorganized speech or negative symptoms
Schizophrenic symptoms for 1-6 months
Schizophreniform symptoms
Schizophrenic symptoms for >6 months
Schizophrenia
Schizophrenic symptoms
Brief Psychotic episodes
Relative Risk?
Exposed Risk/Unexposed Risk
Number needed to treat is opposite of the?
absolute risk reduction value
Absolute Risk Reduction?
Percentage of mortality in Conventional-Percentage of mortality in Novel
Headache, altered level of consciousness and increased signalling in the temporal lobe?
Encephalitis
MCC of viral Encephalitis?
HSV
MC Porphyria?
Porphyria cutanea tarda
Acute Intermittent Porphyria, enzyme and accumulation?
Hydroxymethylbilane (HMB) synthase
Porphobilinogen
Porphyria Cutanea Tarda, enzyme and accumulation?
URO decarboxylase
Uroporphyrinogen
What diseases have Anticipation?
Trinucleotide repeat diseases
Recurrent hemathroses?
Hemophilia
Hemophilia Genetics?
X-linked
Exudate vs transudate fluid
Exudate
Protein>0.5 and Pleural LDH>0.6
Hemolysis in buffered salt solutions?
Osmotic Fragility
Hereditary Sphercytosis Labs?
Increased MCHC, acidified glycerol test
abnormal eosin 5
Complications of hereditary sphercytosis
Gallstones and aplastic anemia
An elderly alcholic with Shock-like sensation that radiates to the feet and neck, what vitamin def.?
B12
B12 vs Folate deficiency?
Folate does not induce neurologic symptoms
A young patient with difficulty chewing, seeing, What is wrong in this patient?
MG
Which is more common Hyperplastic Tissue vs Thymoma?
Hyperplastic Tissue
How many genes need to deleted in tumor supressor genes? What is this phenomenon called? Examples?
2
2 hit hypothesis
Retinoblastoma
Recurrent Fungal or Viral infections suggest problems in?
T-Cell lymphocyte
Digeorge Syndrome is the failure of the development of?
3rd and 4th pouch
Metabolics associated with DKA?
Metabolic Acidosis, Hyperkalemia, Hyperglycemia, Hyperammoniemia, Hyponatremia
In pheochromocytoma, what drug should you use?
Phenoxybenzamine
