Uworld Exam 11 Flashcards
MC pituitary adenoma in a child?
craniopharyngioma
Anterior pituitary origin?
Rathke’s pouch
Posterior pituitary origin?
neuroectoderm
Craniopharyngioma contains 3 components?
Solid, cystic, calcification
Another word for urge incontinence? MOA?
Gotta Go!
MOA: destrusor muscle instability (overactive bladder)
A patient who has an urge to urinate and cannot make it to the bathroom and pees on herself? Tx?
urge incontinence
Tx: Antimuscarinics
Tricuspid valve is heard best at?
4th ICS at the lower sternal border (parasternal)
Synthesis of multiple, short DNA fragments?
Okazaki Fragments
A patient with Excessive Daytime Sleepiness and Laughter/crying triggers paralysis. Dx? What is undetectable/low in the CSF of this patient?
Narcolepsy
CSF: Hypocretin-1
Where is Hypocretin made and what does it do?
Location: Lateral hypothalamus
Function: promote wakefulness and inhibit REM sleep
A patient feels that the physician resembles his dad in that he was not there for him. Dx?
Transference
Occurrence of multiple phenotypes often in different organ systems as a result of a single genetic defect?
Pleiotropy
Proportion of individuals who express the associated phenotype
Penetrance
Hib vaccine is composed of what? What is it attached to?
capsular polysaccharide
Diptheria/Tetanus
Haemophilus inflenzae type b causes what particular disease?
meninigitis
Obstructive sleep apnea can lead to what two manifestations?
Pul. HTN and R. Heart Failure
Pulsatile Treatment of GnRH is for?
Infertility
Most Hypoosmolar in the nephron?
Early Distal Tubule
Aortic Regurgitation Murmur is best heard where?
Left Sternal Border, patient leaning forward and on expiration
Liver Biopsy shows pigmented inclusions in the lysosomes and the pigments are polymers of epinephrine. What disease?
Dubin Johnson