Uworld – Heme/onc

Question 0

Agammaglobulinemia versus common variable deficiency?

Answer 0

Both have recurrent infections and decreased immunoglobulins

6 months old at presentation versus 15 to 35 years

Question 1

Posterior vermis syndrome – associated with? Symptoms?

Answer 1

Medulloblastoma; truncal dystaxia

Question 2

Proposed mechanism for hemophilic arthropathy?

Answer 2

Iron deposition, synovial thickening with fibrosis

Question 6

Sx of polycythemia in newborns?

Answer 6

1. Respiratory distress, tachypnea, cyanosis (decreased pulmonary blood flow due to hyperviscosity)
2. Hypoglycemia, hypocalcemia

Question 7

Howell-Jolly bodies – stain? Remnants of?

Answer 7

Wright stain. Nucleated remnants within red blood cells

Question 8

Juvenile angiofibroma - Sx?

Answer 8

Epistaxis, localized mass, bone erosion on the back of nose

Question 9

Craniopharyngioma versus pituitary adenoma

Answer 9

Calcified lesion above the sella, diabetes insipidus, hypothyroidism, growth hormone deficiency versus prolactinoma and no calcification