Uworld 2 Flashcards

1
Q

Temporal arteritis cytokine

A

IL-6

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2
Q

drugs for drug-induced lupus

A

hydralazine
procainamide
isoniazid

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3
Q

daptomycin MOA and side effects

A

depolarizes cell membrane w/ channels

–> myopathy

inactivated by pulmonary surfactant.

used for MRSA

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4
Q

enteropeptidase does what?

A

activates trypsin –> protein and fat digestion

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5
Q

risedronate MOA

A

this is a bisphophonate
inhibits mature osteoclast-mediated bone resorption

increases osteoclast apoptosis

decreases dev’t of osteoclast precursors

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6
Q

reactive arthritis serum finding

A

HLA-B27

NOT rheumatoid factor

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7
Q

budding yeasts with thick capsules

A

cryptococcus neoformans

manifests as eningoencephalitis

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8
Q

lithium in pregnancy –>

A

Ebstein’s anomaly: apical displacement of the tricuspid valve, atrialization of the right ventricle

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9
Q

path of neisseria meningitis infection

A

pharynx–> blood–> choroid plexus–> meninges

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10
Q

vWF

A

binds glycoprotein Ib receptors
carrier for factor VIII

defish –> mucocutaneous bleeding, poor platelet aggregation int eh presence of ristocetin

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11
Q

2 main causes of ectopic preggers

A

gonorrhea and chlamydia

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12
Q

what do cephalosporins bind to?

A

transpeptidases

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13
Q

what part of ECG do beta blockers work on?

A

prolong PR interval

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14
Q

calcium and PTH levels in primary osteoporosis

A

all normal

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15
Q

vitamin A defish

A

night blindness
corneal ulceration
hyperkeratosis
growth retardation

causes: pancreatic, cholestatic/ biliary, malabsorption

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16
Q

what cells would we find in the lavage fluid in sarcoidosis?

A

CD4+ T cells

17
Q

Lambert Eaton Syndrome goes with

A

lung cancer

and sometimes autonomic issues (dry mouth, impotence)

18
Q

xeroderma enzyme

A

endonuclease

19
Q

first line treatment for acute gouty arthritis

A

NSAIDS

20
Q

strongest risk factor for cervical dysplasia/ carcinoma

A

HPV infection

immunosuppressed can be the other way of saying this