sim ex 1b Flashcards
Krukenberg tumor
metastatic adenocarcinoma in the ovary
most likely from stomach
treatment for diabetic gastroparesis
metoclopramide
cyanide
binds the ferric iron in cytochrome oxidase (Complex IV)
–> smell of burnt almonds on breath
clozapine
atypical antipsychotic that blocks D4, 5-HT2, muscarinic and alpha-1 receptors
effective at treating the negative symptoms of schizophrenia and is used in patients unresponsive to traditional therapies
associated with the development of severe antimuscarinic effects, agranulocytosis, neuroleptic malignant syndrome, tardive dyskinesia, and cardiac arrest
thin, gray vaginal discharge with positive whiff test
gardnerella vaginalis
“the old man who smokes and drinks and has rotten teeth,” prime candidate for
squamous cell carcinoma of the head and neck mucosa
foot drop and high-stepping gait are caused by damage to what nerve?
deep peroneal
arises from common peroneal and innervates the anterior muscles of the leg
histrionic personality disorder
conspicuous seeking of attention consciousness of appearance dramatic presentation multiple unstable relationships acting without thinking making rash decisions unexpected sexual overtones
taking exogenous androgens –>
negative feedback to reduce GnRH
- -> decreased LH and FSH
- -> decreased testosterone production in Leydig cells, testicular atrophy
equation for MAP
COxPVR
Amiodarone
class III antiarrhythmic agent, prolongs myocardial cell action potential during the refractory period
used in the treatment of refractory ventricular tachycardia and supraventricular tachycardia
associated with thyroid dysfunction, paresthesias, pulmonary fibrosis, cardiac arrhythmias, and heart failure
pseudomonas aeruginosa
gram-eg
encapsulated
contaminates burns
DIC via endotoxin (LPS in outer membrane) that activates acrophages to overproduce IL-1, IL-6, and TNF-alpha
also produces exotoxin A (inhibits protein synthesis by ribosylating eukaryotic elongation factor-2)
thiazide diuretics and urine flow rate
thiazide diruretics decrease urine flow rate by increasing reabsorption of solutes and water from the proximal tubule.
stuff that goes with Marfan
mutation in FBN-1 (codes fibrillin-1)
fibrillin-1 helps elastin organize into elastic fibrils
elongated bones, lens dislocation (suspensory ligament weakness), AORTIC ROOT dilation,
stuff that goes with Tay-Sachs
deficiency of hexosaminidaseA lysosomal storage disease Ashkenazi Jews GM2 accumulates in CNS weakness, retardation, blind, die by 3 cherry-red spot on the macula
increased GALACTOCEREBROSIDE
