Uveitis Flashcards

1
Q

Describe the different types of classifications of uveitis.

A

TAPE:

T - Temporal (time)
A - Anatomical
P - Pathological
E - Etiological

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2
Q

Subdivide the Temporal (time) classification of uveitis.

A

Acute (less than 6 weeks), chronic (more than 6 weeks), or recurrent.

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3
Q

Subdivide the Anatomical classification of uveitis.

A

Anterior - Iritis/ iridocyclitis
Intermediate - Pars plantis (pars plana of ciliary body)
Posterior - Posterior vitreous base
Pan-uveitis - Everything

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4
Q

Subdivide the Pathological classification of uveitis.

A

Granulomatous/ Non-Granulomatous

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5
Q

Subdivide the Etiological classification of uveitis.

A

Exogenous/Endogenous/Idiopathic

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6
Q

Etiology of Anterior uveitis?

A

Sickness Of I’s (2 Eyes)

S- Systemic
O - Ocular problems
I - Idiopathic
I - Infections

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7
Q

Etiology of Anterior uveitis - elaborate on systemic causes.

A

27 JoBS
27 - HLA 27 - PAIR (Psoriatic arthritis, Ankylosing Spondylitis, IBD, Reiter)
J - JRA
o
B -Bechet (lesions in genitalia, Uveitis, lesions in mouth)
S - Sarcoidosis

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8
Q

Etiology of Anterior uveitis - elaborate on Ocular problems.

A

“Fuck the eyes upfront”- Fuchs heterochromatic iridocyclitis

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9
Q

Etiology of Anterior uveitis - elaborate on Infections.

A

TB, HSV, VZV, Syphilis

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10
Q

Anterior Uveitis findings:

A

Anterior Uveitis loves KFC’S Nodules!

K - Keratopercipitants (on the endothelium)
F - Flare and cells
C - Ciliary injection
S - Synechea (posterior - flower pupil in kids)

Nodules - on the Iris (Sarcoidosis)

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11
Q

Anterior Uveitis findings - Ciliary injection not affected with

A

Phenylephrine. Ciliary injection manifested from deep vessels, and Phenylephrine superficial vessels.

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12
Q

Anterior Uveitis symptoms:

A

PR VAT

P - Photophobia
R - Redness

V - Vision decreased
A - Algia (pain)
T - Tears (lacrimaion)

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13
Q

Keratopercipitants (on the endothelium) due to VZV are_____.

A

small.

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14
Q

Keratopercipitants (on the endothelium) due to granulomatous disease are_____.

A

Big (mutton fat)

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15
Q

Fresh vs Old Keratopercipitants (on the endothelium) visual characteristics:

A

Fresh - white and rouns

Old - dark and shriveled.

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16
Q

Nodules on the Iris cause____, which leads to____, and relieved with____.

A

inflammation of the pupillary muscle, photophobia, cyclopentolate,

17
Q

Flare and cells are ranked by_____.

A

The number of cells.

Ranks are 1-4 (above 50 cells= rank 4)

18
Q

Dilating the pupil of a patient with posterior synechea may lead to ____.

A

Rupture of the Iris and pigment stuck on the lens.

19
Q

Intermediate (Pars plantis) Uveitis pathophysiology:

A

Ciliary body inflammation -> cytokines and inflammation factors -> Cystoid macular edema.

20
Q

Intermediate (Pars plantis) Uveitis symptoms:

A

Sudden vision loss and/or floaters (vitreous full of percipitans)

21
Q

Intermediate (Pars plantis) Uveitis findings:

A

The anterior segment is fine, CME with snow banking (white parts), Vitrits (cells in the vitreous)

22
Q

Intermediate (Pars plantis) Uveitis treatment:

A

Posterior sub-tenon steroids.

23
Q

Posterior Uveitis findings:

A

CV3R:

C - Choroid lesion (elevated lesions on the retina)
V - Vasculitis
V - Vitreous has cells
V - Vitreous has snowballs
R - Retinitis
24
Q

Posterior Uveitis symptoms:

A

Sudden vision (fovea/papilomacular bundle) loss and/or floaters.

25
Q

Posterior Uveitis etiology:

A

I SIN

I - Idiopathic
S - Sympathetic ophthalmia
I - Infections
N - Non-infectious

26
Q

Etiology of Posterior uveitis - elaborate on Infections.

A

T3H2C2S1 (THC’S)

T - Toxocara, Toxoplamosis, TB
H - HSV, Histoplamosis
C - CMV, Candida
S - Syphilis

27
Q

Posterior Uveitis findings - elaborate on shapes.

A

THC

Toxoplamosis - unifocal
Histoplasmosis - multifocal
CMV - geografic

28
Q

Uveitis workup:

A
IMP(EACH)2 Syphilis:
I - IM rheumatology consult
M - Mantoux (and acid fast bacili sputum) for TB
P - PCR for HSV
E - ESR/ELISA (Toxocara and Toxoplamosis - "Elisa has TT's")
A - ACE (sarcoid)/ ANA,ANCA (Wegner)
C - CT (sarcoid/TB)/ CBC
H - HLA (B27/29)/HIV
Syphilis - VDRL/TPHA
29
Q

Uveitis treatment:

A

CC’S

S - Steroids EARLY (topical, ocular injections, systemic) with antibiotic\antivirals.
C - Cyclopegics for pain and photophobia
C - Cytotoxics (Cyclosporis, Cyclophosphamide, MTX, Azathioprine), for non-reacting posterior uveitis.

30
Q

Chronic Uveitis complications:

A

RV SCuMBaG!

R - Retinal neovascularization
V - Vitreous opacities
S - Synechiae
C - Cataract
M - Macular edema
B - Band keratopathy 
G - Glaucoma
31
Q

Retinal neovascularization treatment:

A

Bevacizumab=Avastin

32
Q

Band keratopathy treatment:

A

EDTA

33
Q

Band keratopathy pathophysiology:

A

Calcium precipitates