Uveitis Flashcards
Describe the different types of classifications of uveitis.
TAPE:
T - Temporal (time)
A - Anatomical
P - Pathological
E - Etiological
Subdivide the Temporal (time) classification of uveitis.
Acute (less than 6 weeks), chronic (more than 6 weeks), or recurrent.
Subdivide the Anatomical classification of uveitis.
Anterior - Iritis/ iridocyclitis
Intermediate - Pars plantis (pars plana of ciliary body)
Posterior - Posterior vitreous base
Pan-uveitis - Everything
Subdivide the Pathological classification of uveitis.
Granulomatous/ Non-Granulomatous
Subdivide the Etiological classification of uveitis.
Exogenous/Endogenous/Idiopathic
Etiology of Anterior uveitis?
Sickness Of I’s (2 Eyes)
S- Systemic
O - Ocular problems
I - Idiopathic
I - Infections
Etiology of Anterior uveitis - elaborate on systemic causes.
27 JoBS
27 - HLA 27 - PAIR (Psoriatic arthritis, Ankylosing Spondylitis, IBD, Reiter)
J - JRA
o
B -Bechet (lesions in genitalia, Uveitis, lesions in mouth)
S - Sarcoidosis
Etiology of Anterior uveitis - elaborate on Ocular problems.
“Fuck the eyes upfront”- Fuchs heterochromatic iridocyclitis
Etiology of Anterior uveitis - elaborate on Infections.
TB, HSV, VZV, Syphilis
Anterior Uveitis findings:
Anterior Uveitis loves KFC’S Nodules!
K - Keratopercipitants (on the endothelium)
F - Flare and cells
C - Ciliary injection
S - Synechea (posterior - flower pupil in kids)
Nodules - on the Iris (Sarcoidosis)
Anterior Uveitis findings - Ciliary injection not affected with
Phenylephrine. Ciliary injection manifested from deep vessels, and Phenylephrine superficial vessels.
Anterior Uveitis symptoms:
PR VAT
P - Photophobia
R - Redness
V - Vision decreased
A - Algia (pain)
T - Tears (lacrimaion)
Keratopercipitants (on the endothelium) due to VZV are_____.
small.
Keratopercipitants (on the endothelium) due to granulomatous disease are_____.
Big (mutton fat)
Fresh vs Old Keratopercipitants (on the endothelium) visual characteristics:
Fresh - white and rouns
Old - dark and shriveled.
Nodules on the Iris cause____, which leads to____, and relieved with____.
inflammation of the pupillary muscle, photophobia, cyclopentolate,
Flare and cells are ranked by_____.
The number of cells.
Ranks are 1-4 (above 50 cells= rank 4)
Dilating the pupil of a patient with posterior synechea may lead to ____.
Rupture of the Iris and pigment stuck on the lens.
Intermediate (Pars plantis) Uveitis pathophysiology:
Ciliary body inflammation -> cytokines and inflammation factors -> Cystoid macular edema.
Intermediate (Pars plantis) Uveitis symptoms:
Sudden vision loss and/or floaters (vitreous full of percipitans)
Intermediate (Pars plantis) Uveitis findings:
The anterior segment is fine, CME with snow banking (white parts), Vitrits (cells in the vitreous)
Intermediate (Pars plantis) Uveitis treatment:
Posterior sub-tenon steroids.
Posterior Uveitis findings:
CV3R:
C - Choroid lesion (elevated lesions on the retina) V - Vasculitis V - Vitreous has cells V - Vitreous has snowballs R - Retinitis
Posterior Uveitis symptoms:
Sudden vision (fovea/papilomacular bundle) loss and/or floaters.
Posterior Uveitis etiology:
I SIN
I - Idiopathic
S - Sympathetic ophthalmia
I - Infections
N - Non-infectious
Etiology of Posterior uveitis - elaborate on Infections.
T3H2C2S1 (THC’S)
T - Toxocara, Toxoplamosis, TB
H - HSV, Histoplamosis
C - CMV, Candida
S - Syphilis
Posterior Uveitis findings - elaborate on shapes.
THC
Toxoplamosis - unifocal
Histoplasmosis - multifocal
CMV - geografic
Uveitis workup:
IMP(EACH)2 Syphilis: I - IM rheumatology consult M - Mantoux (and acid fast bacili sputum) for TB P - PCR for HSV E - ESR/ELISA (Toxocara and Toxoplamosis - "Elisa has TT's") A - ACE (sarcoid)/ ANA,ANCA (Wegner) C - CT (sarcoid/TB)/ CBC H - HLA (B27/29)/HIV Syphilis - VDRL/TPHA
Uveitis treatment:
CC’S
S - Steroids EARLY (topical, ocular injections, systemic) with antibiotic\antivirals.
C - Cyclopegics for pain and photophobia
C - Cytotoxics (Cyclosporis, Cyclophosphamide, MTX, Azathioprine), for non-reacting posterior uveitis.
Chronic Uveitis complications:
RV SCuMBaG!
R - Retinal neovascularization V - Vitreous opacities S - Synechiae C - Cataract M - Macular edema B - Band keratopathy G - Glaucoma
Retinal neovascularization treatment:
Bevacizumab=Avastin
Band keratopathy treatment:
EDTA
Band keratopathy pathophysiology:
Calcium precipitates