Systemic disease and the eye Flashcards
Hypertensive retinopathy pathophysiology:
Problems with autoregulation of blood flow in the precapillary and capillary lead to ischemia.
Hypertensive retinopathy grading:
0-4
Hypertensive retinopathy grade 0 finding:
No change
Hypertensive retinopathy grade 1 finding:
Minimal arterial narrowing (segmental or the entire vessel)
Hypertensive retinopathy grade 2 finding:
Venous narrowing at AV crossing
Hypertensive retinopathy grade 3 finding:
DBP of 110
Retinal bleeding (dot, Blot, Flame)
Cotton wool spot
NO microaneurysms.
Hypertensive retinopathy grade 4 finding:
DBP 130, SBP 200
Swollen disc
Contrary to diabetic retinopathy, there are no_____ in Hypertensive retinopathy.
no microaneurysms.
changes in ____ grades are due to chronic hypertension, and changes in _____grade are due to acute hypertension
changes in 1-2 grades are due to chronic hypertension, and changes in 3-4 grades are due to acute hypertension
______ Blood pressure is more important for RF
DBP
In the 3-4 hypertensive retinopathy grades there is _____ involvement, that can lead to ______
Choroidal, RD due to fluid escaping (serotic)
Can VA remain damaged after signs have passed?
Yes, especially damage to ON, macula, RPE
Graves ophthalmopathy - the percentage of hypo, EU, and hyper thyroidsim.
5% - EU
1% - hypo
Above 90% - hyper
Graves ophthalmopathy - There is a correlation between the degree of thyroid disease and the degree of ophthalmopathy. True/False?
False! There is NO correlation between the degree of thyroid disease and the degree of ophthalmopathy.
Graves ophthalmopathy - ocular involvement can be remembered through _____.
NO SPECS:
N - no signs
O - Only signs
S - Soft tissue P - Proptosis E - Extraocular muscles involvement C - Corneal damage S - sight loss
Graves ophthalmopathy - What is the soft tissue involvement?
Lids: lid lag, lid swelling
Conjunctiva: not diffuse (at the insertion of the muscles)
Graves ophthalmopathy - Extraocular muscles involvement is progress in what pattern?
Starts at the IR and continues in a counter-clockwise fashion.
Graves ophthalmopathy - Extraocular muscles involvement pathology?
May lead to?
Spindle hypertrophy and doesn’t involve the tendons, and may lead to diplopia.
Graves ophthalmopathy - Corneal damage pathophysiology?
Exposure keratopathy (SPK is usually seen)
Graves ophthalmopathy - sight loss is due to _____
Pressure on the ON
Graves ophthalmopathy - therapy:
דרדס
דמעות
רדיולוגי
דה-קומפרסיה
סטרואידים
RA ophthalmopathy - ocular involvement can be remembered through _____.
Dry CURVES
Dry - kertocunjictivitis sicca C - Choroiditis U - Ulceration R - RD V - Vasculitis E - Episcleritis S - Scleritis
Kertocunjictivitis sicca - Dx?
Schirmer dry eye test - <5mm in 5 minutes
Kertocunjictivitis sicca - Tx?
Tear replacement, Punctum plug
Episcleritis vs Scleritis finding?
The 5 P's - Scleritis presents with: P - Pain P - Purple (red-purple) P - Photophobia P - profound (deep) vessel involvement P - Phenyephrine test positive
Scleritis can be seen with?
WIPS: W - Wegner I - IBD P - PAN S - SLE
Scleritis mandates _____.
systemic review
Episcleritis vs Scleritis vs Nec. Scleritis finding Tx.
Episcleritis - Tears + NSAIDS/ Steroid drops
Scleritis - systemic steroid therapy.
Nec. Scleritis - surgical with immunosuppressive and cytotoxic therapy.
Corneal ulceration Tx:
surgical, steroids, cytotoxic therapy.
JRA uveitis- % of uveitis, and most common type of JRA
80%, Pauciarticular.
JRA uveitis - possible complications
CaGeS:
C - Cataracts
G - Glaucoma
S - Sight loss
JRA uveitis - signs:
K-SHIP: K - Kerato-precipitants (KP, on the endothelial side) S - Sight loss H - Hypopion I - IOP P - Pain
JRA uveitis - Tx:
Steroids and Cycloplegia (to prevent posterior synechiae)
Spondyloarthropathies uveitis percentage involvement?
RAPI! R - Reiter, 40% A - Ankylosis spondylitis, 25% P - Psoriatic arthritis, 20% I - IBD, 10%
Important milestones:
2 months (6-8 weeks) - social smile
2.5 months (8-10 weeks) - 180 degree follow
2-3 months - fixation reflex
4 months - reaching attempts
Children vision analysis?
BS CHiC B - Behavior fixation S - Shaps usage C - Cards (acuity) H - HOTV C - Chart (snellen)
Bad signs regardind children vision loss:
Light WORN:
Light indifference
W - Wandering eye movements
O - Oculodigital sign
R - Response lacking
N - Nystagmus
Phoria VS Tropia
Phoria - only in specific situations
Tropia - most of the time (can be intermittent or constant)
Strabismus - light reflex tests:
Hirshberg test and krimsky test
Hirshberg test - every 1 mm means a deviation of_____
7 degrees or 15 prism diopters
Pseudo-Strabismus happens when____
difference of epicanthal folds
Strabismus workup tests:
light reflex tests or cover/uncover test or mix.
Congenital vs acquired strabismus:
before or after 6 months
Fixation behavior strabismus classification:
Alternating fixation - both eyes display strabismus.
monocular fixation - only one eye fixates.
Strabismus etiologies:
CAIR: Congenital A - Accommodative I - Idiopathic R - Restrictive
Strabismus workup:
FARMS: F - Fundoscopy A - Accuity R - Refraction M - movement exam S - Slit lamp
Two common pathologies leading to strabismus:
Rb and Occilcutaneus albinism
Every _____ finding mandates an ophthalmology exam
Strabismus
Accommodative esotropia pathophysiology:
Hypermetropia (+2 to +10) -> Accommodation + Miosis + Convergence -> esotropia
Accommodative esotropia peak onset:
Age
2-3 years old.
Accommodative esotropia Tx:
Glasses.
Congenital esotropia mnemonic
“Most common Uppedy BItCH”
The most common type of strabismus.
Vertical componnent (UP)
B - Bilateral
I - Idiopathic
C - Cross fixation
H - Hypermetropia
Congenital exotropia is accompanied by ___ and thus mandates ____
EXotropia has EXtra stuff.
Many systemic, Neurologic, structural (skull) diseases. Pediatric neurologist and imaging (CT or MRI)
Intermittent exotropia is a type of ____ strabismus
Divergent
When does Intermittent exotropia usually present?
6 months to 4 years
Intermittent exotropia goes away when looking at ______
nearby objects
Intermittent exotropia - indications for surgery
DICk
D - Depth vision loss
I - Incidence increase (above 50%)
C - Close object exotropia
Strabismus Tx:
The BG’S
B - Botox
G - Glasses (prism/accommodation)
S - Surgery (Resection/Recession)
Amblyopia etiologies:
SAD I (eye)
S - Strabismic
A - Anisometropic
D - Deprivation of sensory info (most common)
I - Isometropic
Amblyopia Tx:
PULP: P - Patch U - Underlying cause L - Lens P - Penaziation (Atropin, unfitting glasses)
Sensory deprivation Amblyopia common position of the kid
chin-up
Sensory deprivation Amblyopia common position of the kid
chin-up
Anisometropic amblyopia - amblyopia is worse with hyperopia or myopia?
hyperopia
Amblyopia is seen when there is VA difference between the eye that is at least ______
VA difference between the eye that is at least 2 rows
Amblyopia incidence in the general population?
2.5%
Amblyopia - what is the critical period?
The period at which the child should have a clear image projected on both retinas together - allows for the proper maturation of the visual brain.
From a week to the first months of life.
Amblyopia - what is the amblyopic period?
The period at which the maturation of the visual brain is complete.
About 7-8 years of age.