UTIs

Question 1

Upper UTI

Answer 1

Pyelonephritis (inf. of kidney/renal pelvis)

Question 2

Lower UTI

Answer 2

Cystitis/prostatitis (inf. of bladder/prostate)

Question 3

Complicated UTI

Answer 3

Prsence of factors that inc. risk of treatment failure
- DM
- Catheter
- stones
- transplant

Question 4

Uncomplicated UTI

Answer 4

if UTI in healthy, non-pregnant adult woman

Question 5

Bacteria that causes UTI

Answer 5

E.Coli
Extended spectrum beta lactamase producing E.Coli (resistant to B lactam Abx)

Question 6

what type of bacteria is E.coli

Answer 6

Gram +ve bacillus

Question 7

CFs

Answer 7

Cystitis
Acute pyelonephritis
Prostatitis
Pyuria

Question 8

Pathophys

Answer 8

• Bacterial colonisation
• E.Coli contain fimbrae - Inc adherence to epithelium, which inc. their survival

Question 9

Ix

Answer 9

pyuria +/- bacteriuria
- Urinalysis:
- Leucocyte esterase (released by WBC)
- Nitrites (pathogens convert nitrates to nitrites)

Question 10

Mgx of uncomplicated UTI

Answer 10

-Cystitis:
Abx:
Trimethroprim and nitrofurantoin

• Pyelonephritis:
  fluoroquinolone (e.g. ciprofloxacin)

Question 11

Mgx of complicated UTI

Answer 11

• Cystitis:
  fluoroquinolone
• pyelonephritis/urosepsis:
  Co-amoxiclav