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Paper 2 > OA > Flashcards

OA Flashcards

1
Q

Osteoarhthritis

A

degenerative disorder
“wear and tear”

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2
Q

Joints mainly affected

A

Knees
Hips
Hands

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3
Q

Pathophys

A

Continuous wear on joints thin the articular cartilage.

Leads to loss of joint space and pain

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4
Q

Synovium cells

A

Type A - clear cellular debris

Type B - secrete synovial fluid

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5
Q

Articular cartilage

A

Chondrocyte (contains T2 collagen) - produces cartilage

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6
Q

caused by

A

Mechanical abnormality
Biochemical abnormality - inc IL-1, TNF-a ( will inc. cartilage metab.)

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7
Q

Ix

A

Radiology - “LOSS”
Loss of joint space
Osteophytes
Subchondral cysts
Sclerosis
Bloods - CRP & ESR

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8
Q

Mgx

A

Exercise
weight loss
physio
paracetamol +/- NSAIDs
Topical capcaisin
Steroid inj.
Arthroplasty

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9
Q

complications

A

gout
chondrocalcinosis

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Paper 2 (23 decks)

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