UTI Flashcards

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1
Q

Describe the fevers for lower UTI vs upper UTI (pylo)

A

low fever/low UTI and high fever/upper UTI

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2
Q

Sxs of UTI resemble what other type of infx?

A

STI

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3
Q

three UTI sxs?

fever/hypothermia
poor feeding
jaundice

A

newborn UTI

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4
Q

What age presents with the below three sxs?

vomiting
diarrhea
poor feeding

A

infant UTI

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5
Q

What age presents with the below five UTI sxs?

irritability
eating poorly
unexplained fever
loss of bowel control
change to normal urinary habit
A

Child UTI

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6
Q

What are the two types of URI-Cult?

A

CLED and EMB

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7
Q

EMB contains bile salts and is selective for…

A

G- TUI pathogens

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8
Q

CLED is selective for _____ and determines the ability to ferment ________

A

selective for G+ and G-

ability to ferment lactose

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9
Q

What is the best way to dx UTI?

A

UA w/ microscopy

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10
Q

Culture is typically done in what population? What number of CFU is diagnostic?

A

men/children, 5x10^4

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11
Q

What additional exam should be done with men suspected of UTI?

A

DRE

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12
Q

What cases necessitate imaging for UTI?

A

children, recurrent infx, hematuria

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13
Q

What agent is responsible for 75-90% of all UTIs?

A

E. Coli

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14
Q

What are the 4 G- causes of UTI?

A

Proteus, Klebsiella, E. Coli, Pseudomonas

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15
Q

What are the three G+ causes of UTI?

A

Enterococcus, Staphy saprophyticus, Group B Strep

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16
Q

What UTI pathogen?

  • G- enteric bacillus
  • flagellated
  • UPEC causes UTI
A

E. Coli

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17
Q

what strains of E. coli are associated with meningitis? When is that possible?

A

K1 encapsulated strain after neurosurgical trauma

18
Q

UPEC E. coli use what to virulence factors to bind uroepithelial cells and erythrocytes?

A

P fibriae and Dr. adhesins

19
Q

UPEC E. coli produce what substances that result in RBC and uroepithelial lysis?

A

alpha and beta hemolysins

20
Q

UPEC E. coli can produce what antigen seen in upper and chronic UTI that results in increased biofilm formation?

A

K antigen

21
Q

What UTI pathogen?

  • G-
  • swarming on culture agar
  • possess fimbriae
  • can be part of normal human flora
  • found in long-term care and hospitals
A

Proteus, P. vulgaris/P. mirabilis

22
Q

P. vulgaris typically infects what patient population?

A

immunocompromised

23
Q

P. mirabilis is acquired how?

A

community acquired

24
Q

Proteus spp can be isolated from hospital staff by swabs of…

A

oral cavity and nasopharynx

25
Q

Proteus uses what structure to bind uroepithelial cells?

A

fimbriae

26
Q

Can proteus cause sepsis?

A

yes

27
Q

Proteus produces ________ to make urine more alkaline, resulting in _______

A

urease, struvite stones

28
Q

What UTI pathogen?

  • G+
  • Coag Neg
  • Normal flora of female GU
  • 2nd leading cause
A

S. saprophyticus

29
Q

This UTI pathogen can occur 24 horus after sex, manifesting with razor sharp pains during intercourse. Called “honeymoon cystitis”

A

S. saprophyticus

30
Q

S. Saprophyticus isn’t very virulent. It doesn’t contain exotoxins, but it dose possess what?

A

adhesins (lactosamine)

31
Q

What differentiates S. saprophyticus from other Coag neg staph?

A

novobiocin resistane

32
Q

Which UTI pathogen?

G+ coccus
gray-white colonies
narrow zone B-hemolysis

A

S. agalactiae (GBS)

33
Q

Where does S. agalactiae colonize making prevention of disease difficult

A

vagina, GI, upper respiratory

34
Q

infx of s. agalactiae in adults is linked with…

A

immunodeficiency

35
Q

Transmission of s. agalactiae from mothers to neonates is…

A

50%

36
Q

the below four virulence factors are present on…

capsular polysaccharide
hyaluronidase
collagenase
hemolysin

A

s. agalactiae

37
Q

Presumptive lab tests for S. agalactiae relies on detection of…

A

CAMP factor (hemolysis accentuation)

38
Q

Definitive Dx of S. agalactiae relies on osilation form…

A

urine, blood, CSF

39
Q

Prostatitis requires what modification of the course of tx from cystitis?

A

longer course

40
Q

What is an indication for hospitalization for UTI…

A

Pyelo +

pregnant, no improvement, immunocompromised, N/V, previous kidney dz, stones, catheter