UTI Flashcards

1
Q

Describe the fevers for lower UTI vs upper UTI (pylo)

A

low fever/low UTI and high fever/upper UTI

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2
Q

Sxs of UTI resemble what other type of infx?

A

STI

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3
Q

three UTI sxs?

fever/hypothermia
poor feeding
jaundice

A

newborn UTI

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4
Q

What age presents with the below three sxs?

vomiting
diarrhea
poor feeding

A

infant UTI

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5
Q

What age presents with the below five UTI sxs?

irritability
eating poorly
unexplained fever
loss of bowel control
change to normal urinary habit
A

Child UTI

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6
Q

What are the two types of URI-Cult?

A

CLED and EMB

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7
Q

EMB contains bile salts and is selective for…

A

G- TUI pathogens

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8
Q

CLED is selective for _____ and determines the ability to ferment ________

A

selective for G+ and G-

ability to ferment lactose

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9
Q

What is the best way to dx UTI?

A

UA w/ microscopy

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10
Q

Culture is typically done in what population? What number of CFU is diagnostic?

A

men/children, 5x10^4

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11
Q

What additional exam should be done with men suspected of UTI?

A

DRE

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12
Q

What cases necessitate imaging for UTI?

A

children, recurrent infx, hematuria

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13
Q

What agent is responsible for 75-90% of all UTIs?

A

E. Coli

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14
Q

What are the 4 G- causes of UTI?

A

Proteus, Klebsiella, E. Coli, Pseudomonas

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15
Q

What are the three G+ causes of UTI?

A

Enterococcus, Staphy saprophyticus, Group B Strep

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16
Q

What UTI pathogen?

  • G- enteric bacillus
  • flagellated
  • UPEC causes UTI
A

E. Coli

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17
Q

what strains of E. coli are associated with meningitis? When is that possible?

A

K1 encapsulated strain after neurosurgical trauma

18
Q

UPEC E. coli use what to virulence factors to bind uroepithelial cells and erythrocytes?

A

P fibriae and Dr. adhesins

19
Q

UPEC E. coli produce what substances that result in RBC and uroepithelial lysis?

A

alpha and beta hemolysins

20
Q

UPEC E. coli can produce what antigen seen in upper and chronic UTI that results in increased biofilm formation?

21
Q

What UTI pathogen?

  • G-
  • swarming on culture agar
  • possess fimbriae
  • can be part of normal human flora
  • found in long-term care and hospitals
A

Proteus, P. vulgaris/P. mirabilis

22
Q

P. vulgaris typically infects what patient population?

A

immunocompromised

23
Q

P. mirabilis is acquired how?

A

community acquired

24
Q

Proteus spp can be isolated from hospital staff by swabs of…

A

oral cavity and nasopharynx

25
Proteus uses what structure to bind uroepithelial cells?
fimbriae
26
Can proteus cause sepsis?
yes
27
Proteus produces ________ to make urine more alkaline, resulting in _______
urease, struvite stones
28
What UTI pathogen? - G+ - Coag Neg - Normal flora of female GU - 2nd leading cause
S. saprophyticus
29
This UTI pathogen can occur 24 horus after sex, manifesting with razor sharp pains during intercourse. Called "honeymoon cystitis"
S. saprophyticus
30
S. Saprophyticus isn't very virulent. It doesn't contain exotoxins, but it dose possess what?
adhesins (lactosamine)
31
What differentiates S. saprophyticus from other Coag neg staph?
novobiocin resistane
32
Which UTI pathogen? G+ coccus gray-white colonies narrow zone B-hemolysis
S. agalactiae (GBS)
33
Where does S. agalactiae colonize making prevention of disease difficult
vagina, GI, upper respiratory
34
infx of s. agalactiae in adults is linked with...
immunodeficiency
35
Transmission of s. agalactiae from mothers to neonates is...
50%
36
the below four virulence factors are present on... capsular polysaccharide hyaluronidase collagenase hemolysin
s. agalactiae
37
Presumptive lab tests for S. agalactiae relies on detection of...
CAMP factor (hemolysis accentuation)
38
Definitive Dx of S. agalactiae relies on osilation form...
urine, blood, CSF
39
Prostatitis requires what modification of the course of tx from cystitis?
longer course
40
What is an indication for hospitalization for UTI...
Pyelo + pregnant, no improvement, immunocompromised, N/V, previous kidney dz, stones, catheter